[ 700+ Medications · One Test For Life ]

PGx Test Cost — One Price, Lifetime Value

Your DNA never changes — so one pharmacogenomics test covers every medication you will ever take. Here is exactly what a PGx test costs, what insurance pays, and why it pays for itself the first time it prevents a bad prescription.

Start Membership — $89/mo See the Full Breakdown

4.9/5 from 10,000+ verified patients — “For the first time in a decade, I feel like myself again.” — Michael R., Naperville, IL

[ $299 One-Time ][ $89/mo Membership ][ CPT 81479 · 81225–81227 ][ HSA / FSA Eligible ]

The Full PGx Test Cost Breakdown

Medications analyzed by the GenePGx pharmacogenomics test
GenePGx individually $299

One-time purchase — 230+ genes analyzed, a personalized medication guide across 700+ drugs, ready for your doctor.

Gene Matrix Membership — all 11 tests $89/mo

GenePGx is included with your Gene Matrix Membership — along with all 10 other genetic tests. No per-test fees. No surprises. $59/mo billed annually ($712/yr).

Start Membership — $89/mo

[ What The Price Includes ]

230+ Genes

Full Sequencing

CYP2D6, CYP2C19, CYP2C9, VKORC1, SLCO1B1 and 90+ more drug-metabolism genes sequenced with 99.9% accuracy.

700+ Medications

10 Specialties

Personalized guidance across psychiatry, cardiology, oncology, pain management, infectious disease, and more.

Clinician-Ready Report

CPIC Referenced

A report your doctor can act on immediately, with CPIC and DPWG guideline references built in.

Lifetime Value

One Test For Life

Your DNA does not change. Share your report with any provider, anywhere, anytime — no repeat tests needed.

Insurance & CPT Codes

[ Coverage Is Expanding Rapidly ]

Many commercial insurers and Medicare Advantage plans now cover PGx testing, particularly for patients starting antidepressants, anticoagulants, or chemotherapy. We verify your benefits before testing and provide superbills for out-of-network reimbursement.

CPT CodeUsed ForAvg. Reimbursement
81479Unlisted molecular pathology procedure — multi-gene PGx panelsVaries — submit for review
81225CYP2C19 gene analysis — clopidogrel & PPI metabolism$180 – $260
81226CYP2D6 gene analysis — antidepressant & tamoxifen metabolism$180 – $260
81227CYP2C9 gene analysis — warfarin & NSAID sensitivity$180 – $260
81350SLCO1B1 gene analysis — simvastatin myopathy risk$160 – $240

[ Coverage Is Most Likely When ]

  • You take a medication with an FDA pharmacogenomic label
  • You have a history of adverse drug reactions
  • Two or more medications in the same class have failed
  • You are initiating a high-risk medication (warfarin, clopidogrel, TPMT drugs)

Reimbursement rates are estimates based on 2026 Medicare fee schedules and may vary by payer, region, and patient coverage. Check my coverage →

One Test. A Lifetime of Better Prescribing.

Most prescribing is still trial and error — and for millions of people, that cycle takes years. The FDA has already added pharmacogenomic information to over 200 medication labels. A $299 test — or $89/month with 10 other tests included — ends the guessing game for every prescription you will ever receive.

Start Membership — $89/mo About PGx Testing
[ 230+ Genes ][ 700+ Medications ][ Results In 5–7 Days ]

Every Way to Pay

[ HSA · FSA · Insurance · Card ]
HSA / FSA

Pay With Pre-Tax Dollars

Gene Matrix tests and subscriptions are HSA/FSA eligible — pay directly with your HSA or FSA card at checkout. We provide detailed receipts and CPT codes to support reimbursement claims.

Insurance

Expanding Coverage

Many insurance plans cover genetic testing when physician-ordered — PGx in particular for patients starting antidepressants, anticoagulants, or chemotherapy. We verify benefits before testing.

Monthly or Annual

$89/mo or $59/mo

Membership is $89/month billed monthly, or $59/month billed annually ($712/yr) — with GenePGx and 10 other tests included.

30-Day Money Back

Risk-Free Start

All plans come with a 30-day money-back guarantee. If you are not completely satisfied within 30 days, contact us for a full refund — no questions asked. Refunds are not available after your DNA sample has been processed in our lab.

PGx Cost Questions, Answered

[ No Billing Surprises ]
GenePGx is $299 as a one-time individual purchase, or included with the Gene Matrix Membership at $89/month (or $59/month billed annually) along with all 10 other genetic tests. The full panel covers 350+ drugs with 700+ medication guidance.
Coverage is expanding rapidly. Many commercial insurers and Medicare Advantage plans now cover PGx testing, particularly for patients starting antidepressants, anticoagulants, or chemotherapy. We verify your benefits before testing and provide superbills for out-of-network reimbursement.
Common PGx billing codes include 81479 (unlisted molecular pathology procedure for multi-gene panels), 81225 (CYP2C19), 81226 (CYP2D6), and 81227 (CYP2C9). Single-gene analyses typically reimburse $160–$260 each on 2026 fee schedules. We provide CPT codes and detailed receipts to support reimbursement claims.
Yes. Gene Matrix tests and subscriptions are HSA/FSA eligible — you can pay directly with your HSA or FSA card at checkout. We provide detailed receipts and CPT codes to support reimbursement claims.
Your DNA does not change, so your pharmacogenomic profile is relevant for life. One test provides actionable information for every medication you may ever take — which is why it is often called the “one test for life.” Share your report with any provider, anywhere, anytime — no repeat tests needed.
Absolutely. If you’re experiencing side effects or your medications are not providing adequate relief, PGx can help explain why. Your genetic profile may reveal that you are a poor metabolizer of certain drugs, requiring different medications or dosage adjustments.

The Right Drug. The Right Dose. The First Time.

Stop the trial-and-error. Your DNA holds the blueprint for how your body processes medications. One test. Lifetime value.

Start Membership — $89/mo Check My Coverage
[ $299 One-Time Or $89/mo ][ Insurance Pre-Verified ][ HSA / FSA Eligible ]