What’s Analyzed
[ 95+ Genes · 6 Areas ]95+ genes analyzed across 6 areas — each revealing something powerful about how your brain, mood, and mind work.
Mood Disorders
Why do you feel the way you feel? Your genetic risk for depression, anxiety, and mood swings — decoded at the DNA level.
Neurotransmitter Function
The brain chemistry behind everything. How your serotonin, dopamine and GABA genes shape your emotions, motivation, and mental balance.
Stress Response
Why stress hits you harder. Your HPA-axis genetics shape your cortisol response — and how quickly you recover.
Cognitive Function
How your brain performs. Memory, focus, and learning speed — all genetically influenced.
Sleep & Circadian
Why you cannot sleep. Your circadian clock genes reveal why sleep eludes you.
Medication Response
Find meds that work for you. Stop guessing — your genes predict how you respond to antidepressants.
Your mental health has a genetic blueprint
[ Key Genes + Answers ]“Why do antidepressants never seem to work for me?”
[ What the science says ]Up to 99% of people carry at least one pharmacogenomic variant affecting psychiatric medication metabolism. CYP2D6 affects antidepressants like fluoxetine, paroxetine, and venlafaxine. CYP2C19 affects citalopram, escitalopram, and sertraline — among the most prescribed antidepressants in the US. If you’re an ultra-rapid or poor metabolizer, standard doses either do nothing or cause immediate side effects.
GeneMind maps your complete psychiatric pharmacogenomics profile — telling you and your psychiatrist exactly which antidepressants, anxiolytics, and mood stabilizers your biology is most likely to respond to before you spend months on the wrong medication.
“Is my anxiety or depression something I inherited?”
[ What the science says ]BDNF (Brain-Derived Neurotrophic Factor) variants affect how your brain creates new neural connections — lower BDNF activity is strongly associated with depression and treatment resistance. The SERT gene controls serotonin reuptake rates, affecting your baseline mood stability. TPH2 regulates serotonin production in the brain’s raphe nuclei. These are the biological underpinnings that turn stress or life events into clinical depression for some people and not others.
GeneMind identifies your neurogenetic risk factors for mood disorders — providing objective information to help you and your mental health provider make proactive decisions about therapy, lifestyle interventions, and early treatment before a crisis.
“Why am I so much more sensitive to stress than others?”
[ What the science says ]FKBP5 is one of the most studied genes in stress biology — certain variants cause elevated cortisol response to mild stressors, difficulty returning to baseline after stress, and significantly higher PTSD risk after trauma. NR3C1 affects glucocorticoid receptor sensitivity — how strongly your cells respond to stress hormones. COMT affects how quickly your prefrontal cortex degrades dopamine and norepinephrine during stress, influencing your recovery time.
GeneMind’s stress response panel gives you and your therapist a biological map of your stress system — the genetic basis for why mindfulness or exercise works differently for you than for someone else, and which stress management interventions align with your neurogenetics.
How It Works
[ From Swab To Answers ]Your mental wellness kit ships free
A simple at-home collection kit arrives in 2-3 business days. Sterile cheek swab, collection tube, prepaid return envelope, and step-by-step instructions. No appointment, no clinic visit, no blood draw.
A quick cheek swab at home
Swab the inside of your cheek for 30 seconds, cap the tube, seal the prepaid envelope, and drop it in any mailbox. No special preparation, no fasting, no stress.
We analyze 95+ mental health genes
Your sample is processed in our CLIA-certified laboratory. We sequence every gene related to your neurotransmitter function, stress response, mood disorders, cognitive performance, sleep patterns, and psychiatric medication metabolism. Reviewed by board-certified geneticists.
Your mental wellness blueprint
In 5-7 days your comprehensive report is available in your secure portal. Share it with your psychiatrist, therapist, or GP — including your pharmacogenomics profile for psychiatric medications and personalized mental wellness recommendations.
What’s in your report
- Pharmacogenomics profile for psychiatric medications
- Neurotransmitter genetic insights — serotonin, dopamine, GABA
- Stress response & HPA-axis analysis
- Sleep & circadian findings
- Personalized mental wellness plan
- CPIC/FDA references for your prescriber
Included With Your Membership
[ GeneMind + 10 More Tests ]GeneMind is included with your Gene Matrix Membership — along with all 10 other genetic tests. No per-test fees. No surprises.
A standalone panel at typical lab pricing — a separate order, a separate kit, and a report that never updates.
This test individually: $349. With your membership: included at $89/mo (or $59/mo billed annually) along with all 10 other tests.
No per-test fees. No surprises. 30-day guarantee. HSA/FSA eligible.
The gene that finally made sense of it all
[ Verified Results ]“After years of trying different antidepressants with no success, GeneMind revealed I have an MTHFR variant affecting folate metabolism and a serotonin transporter variant. My psychiatrist completely changed my treatment plan. I finally feel stable.”
Aisha M. — Atlanta, GA · MTHFR + SLC6A4 variants identified
Frequently asked
GeneMind analyzes over 95 genetic markers that influence neurotransmitter function, stress response, mood regulation, and medication metabolism. This information helps healthcare providers personalize treatment plans, predict medication responses, and identify risk factors for mental health conditions, leading to more effective and targeted interventions.
No, GeneMind does not diagnose mental health conditions. It identifies genetic predispositions and risk factors that may influence your mental health. This information should be used in conjunction with clinical evaluation by qualified mental health professionals to inform treatment decisions and preventive strategies.
Yes! GeneMind includes pharmacogenomic analysis that examines how your genes affect medication metabolism and response. This can help your healthcare provider select medications that are more likely to be effective for you and avoid those that may cause side effects or be less effective based on your genetic profile.
Absolutely. We take your privacy extremely seriously. Your genetic data is encrypted, stored securely, and never shared with third parties without your explicit consent. We comply with HIPAA, GDPR, and all applicable privacy regulations. You maintain full ownership and control of your genetic information.
GeneMind uses state-of-the-art sequencing technology with 99.2% accuracy. Our analysis is based on peer-reviewed scientific research and validated genetic markers. However, it’s important to remember that genetics is just one factor in mental health—environment, lifestyle, and experiences also play crucial roles.
Your genetic code remains constant, but our understanding of how genes influence mental health continues to evolve. Members receive quarterly updates as new research emerges and our analysis algorithms improve, ensuring you always have access to the latest scientific insights.