[ 5–7 Days · From $89/mo ]

Pharmacogenomics Testing (PGx)

Your DNA determines how you process medications. Our PGx test analyzes 230+ genes covering 700+ drugs so your doctor can prescribe the right medication at the right dose — the first time.

Order Your PGx Test See Medications Covered
[ 230+ Genes Analyzed ][ 700+ Medications Covered ][ CPIC Guidelines ][ CLIA-Certified ]

Key Genes That Affect Your Medications

Medications whose response is guided by pharmacogenomic testing
Metabolizes ~25% Of All Drugs

CYP2D6

Antidepressants, antipsychotics, beta-blockers, opioids, tamoxifen.

Clopidogrel Activation

CYP2C19

Plavix, PPIs, antidepressants, anticonvulsants.

Warfarin Metabolism

CYP2C9

Warfarin, NSAIDs, sulfonylureas, losartan.

Most Abundant Liver Enzyme

CYP3A4

Statins, calcium channel blockers, immunosuppressants.

Statin Uptake Transporter

SLCO1B1

Simvastatin, atorvastatin myopathy risk.

Warfarin Target

VKORC1

Warfarin dosing, bleeding risk.

Thiopurine Metabolism

TPMT

Azathioprine, 6-MP toxicity risk.

Fluoropyrimidine Breakdown

DPYD

5-FU, capecitabine severe toxicity.

700+ Medications Covered

[ If You Take It, We Can Tell You How Your Genes Affect It ]
Psychiatry

Every Major Therapeutic Area

Antidepressants, antipsychotics, mood stabilizers, ADHD meds, anxiolytics.

Cardiology

Every Major Therapeutic Area

Statins, beta-blockers, anticoagulants, ACE inhibitors, antiarrhythmics.

Oncology

Every Major Therapeutic Area

Chemotherapy agents, targeted therapies, immunotherapy, supportive care.

Pain Management

Every Major Therapeutic Area

Opioids, NSAIDs, muscle relaxants, migraine medications, local anesthetics.

Infectious Disease

Every Major Therapeutic Area

Antibiotics, antivirals, antifungals, HIV medications, hepatitis treatments.

Other Therapies

Every Major Therapeutic Area

Gastroenterology, endocrinology, neurology, transplant, immunosuppressants.

How PGx Testing Works

[ From Swab To Prescription Clarity ]
[ 01 ]

Order Your Kit

Start your membership — $89/month. Kit ships within 24 hours.

[ 02 ]

Collect Sample

Simple cheek swab at home. No blood, no needles. Mail back prepaid.

[ 03 ]

DNA Analysis

We sequence 230+ drug-metabolizing genes using NGS technology.

[ 04 ]

Get Your Report

Clinician-ready report with CPIC guideline references. Share with your doctor.

Get PGx with Your Membership

[ No Per-Test Fees. No Surprises. ]
Pharmacogenomics (PGx) individually $499

One-time purchase — a single test, a single report.

Gene Matrix Membership — all 11 tests $89/mo

Pharmacogenomics (PGx) is included with your Gene Matrix Membership — along with all 10 other genetic tests. No per-test fees. No surprises.

Start Membership — $89/mo

This test individually: $499. With your membership: included at $89/mo (or $59/mo billed annually) along with all 10 other tests. Compare all 11 tests

Why Pharmacogenomics Matters

[ The Case For Testing First ]
Adverse Reactions

First Prescriptions

Many patients experience an adverse drug reaction on their first prescription. PGx testing reduces this risk significantly.

Better Outcomes

Genetically Guided

Better treatment outcomes when medications are selected based on genetic profile rather than trial-and-error.

Preventable Deaths

Every Year In The U.S.

Deaths per year in the U.S. from adverse drug reactions that could have been prevented with pharmacogenomic testing.

200+

FDA Medication Labels

FDA-approved medication labels now include pharmacogenomic information — your genes are already part of prescribing.

What Your Report Includes

[ Clinician-Ready, CPIC-Referenced ]
Metabolizer Status Summary

Your Phenotype, Plainly

Poor, intermediate, normal, rapid, or ultra-rapid metabolizer status for every key gene — the summary your doctor reads first.

Medication Guidance

700+ Drugs Covered

A personalized medication guide across 700+ drugs — which to use, which to avoid, and which need a different dose.

Clinical Guidelines Referenced

CPIC & FDA

Clinician-ready report with CPIC guideline references. Report sections: Drug Metabolism, Cardiovascular, Psychiatric, Pain Medications, Oncology, Common Meds.

View a sample report (PDF) ↓

“After years of cycling through antidepressants with terrible side effects, my PGx test revealed I am a CYP2D6 poor metabolizer. My doctor switched me to a genetically appropriate medication. For the first time in a decade, I feel like myself again.”

Michael R. — Naperville, IL · CYP2D6 Poor Metabolizer

PGx Is Just The Beginning

[ Your Subscription Unlocks All 11 Tests ]
Included In Your Plan

GeneMind

Mental health genetics — know which psychiatric medications work for your brain chemistry.

Included In Your Plan

GeneCancer

108-gene hereditary cancer panel to guide oncology drug selection with PGx data.

Included In Your Plan

GenePain

Pain management genetics — optimize opioid and analgesic selection with your PGx profile.

Frequently Asked Questions

[ PGx, Answered ]
Pharmacogenomics (PGx) analyzes your DNA to predict how you will respond to medications. It can tell you which drugs are likely to work, which may cause side effects, and what dose is right for your body. The FDA has added pharmacogenomic information to over 200 medication labels.
Our PGx panel analyzes 230+ genes and covers over 700 medications across all major therapeutic areas including psychiatry, cardiology, oncology, pain management, and infectious disease.
Coverage is expanding rapidly. Many commercial insurers and Medicare Advantage plans now cover PGx testing, particularly for patients starting antidepressants, anticoagulants, or chemotherapy. We verify your benefits before testing and provide superbills for out-of-network reimbursement.
In most states, you can order directly. However, we strongly recommend sharing your results with your prescribing physician so they can use the information to guide your treatment. Our reports are designed to be clinician-ready and include CPIC guideline references.
Results are typically available within 5–7 days from when your sample arrives at our CLIA-certified laboratory. Your report is accessible through a secure online portal.
Yes — your DNA does not change, so your pharmacogenomic profile is relevant for life. One test provides actionable information for every medication you may ever take. This is why it is often called the "one test for life."

The Right Drug. The Right Dose. The First Time.

Stop the trial-and-error. Your DNA holds the blueprint for how your body processes medications. One test. Lifetime value.

Start Membership — $89/mo Talk to a Specialist
[ 230+ Genes ][ 700+ Medications ][ Results In 5–7 Days ]