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Two women, one visibly older, sitting close together on a sofa, smiling at each other with their hands clasped.

One saliva sample. Checks selected variants across 108 genes, including BRCA1 and BRCA2, by genotyping. A clear report to talk through with your doctor.

$399self-pay price

Selected variants only, by genotyping. Not a full-gene test.

One price, paid when you order.

If you or a close relative has had cancer, ask your doctor about full-gene clinical testing.

Buy GeneCancerSee all tests

Have Medicare, Medicaid, TRICARE or another government health plan? Please contact us before you order.

The first year of GeneMatrix+ is included when you turn on automatic renewal at checkout. After that it’s $99 a year until you cancel. Renewal is charged to your payment method each year. Leave automatic renewal off and you get the test alone, without a GeneMatrix+ year. Cancel anytime online, or by writing to info@genematrix.io. Your reports stay yours.

Testing for inherited cancer risk is a screening test, not a diagnosis. Please read the full note

  • Genotyped in our own CLIA-certified lab (New York orders excepted)
  • Your genetic data is never sold, and never shared for marketing or research
  • Reports are yours to keep
  • Full refund within 30 days of ordering, as long as your results haven’t been delivered.

In the family

An inherited variant is passed down, so parents, brothers and sisters, and children can share it. If one is found, your report explains how it is passed on, in words you can share with your relatives and their doctors.

  1. Your parents
  2. You, and your brothers and sisters
  3. Your children

What you’ll learn

A family treeRelatives across three generations drawn as a pedigree, squares and circles joined by lines, as a clinician sketches a family history. No one is marked.

Whether you carry any of the specific inherited variants this panel tests for that are associated with higher cancer risk.

Three closed linen-bound albums stacked on a round wooden side table, tortoiseshell glasses on top, a cup of tea and a sprig of dried lavender beside them.

  • Whether you carry a variant

    The panel checks selected, known variants in each gene it lists, and the report says plainly which of them were found.

  • What a finding is linked to

    If a variant is found, which cancers it is associated with, and how much is known about it.

  • What it could mean for family

    Relatives can share an inherited variant. The report explains how one is passed on, so you can share it with them and their doctors.

  • Questions for your doctor

    The screening questions worth raising, so you and your doctor can plan with more to go on.

Your report

A result reads in three parts: what was found among the variants this panel tests, what that means, and the next step, which is a conversation with your doctor. When none is found, the report says what that does and does not cover, and that the screening your doctor recommends still applies.

See a full sample report

Illustrative, not a real person’s result

GeneCancer · Hereditary cancer

Illustrative example

Result

None of the pathogenic or likely pathogenic variants tested was detected.

What it means
None of the variants this panel tests for was found. The panel does not read every position in these genes, so a variant it does not test for may still be present.
Next step
Keep to the screening your doctor recommends, and bring this report to your next appointment.
Testing for inherited cancer risk is a screening test, not a diagnosis. A result with no variant found does not mean you will not develop cancer, and finding a variant does not mean you will. Talk to your doctor or a genetic counselor before making any decision about screening, medication or surgery.

Ways to buy

One self-pay price, paid once when you order. Results are usually ready 5 to 7 business days after the lab receives your activated sample (10 to 14 business days during holiday weeks).

GeneCancer, self-pay

$399 self-pay price

Self-pay price, paid once

Selected variants only, by genotyping. Not a full-gene test.

  • Saliva, from a gentle swab along your gums at home
  • Checks selected variants across 108 genes, including BRCA1 and BRCA2, by genotyping.

If you or a close relative has had cancer, ask your doctor about full-gene clinical testing.

Buy GeneCancer

One price, paid when you order.

Add to cart: GeneCancer

The first year of GeneMatrix+ is included when you turn on automatic renewal at checkout. After that it’s $99 a year until you cancel. Renewal is charged to your payment method each year. Leave automatic renewal off and you get the test alone, without a GeneMatrix+ year. Cancel anytime online, or by writing to info@genematrix.io. Your reports stay yours.

Have Medicare, Medicaid, TRICARE or another government health plan? Please contact us before you order.

Testing for inherited cancer risk is a screening test, not a diagnosis. A result with no variant found does not mean you will not develop cancer, and finding a variant does not mean you will. Talk to your doctor or a genetic counselor before making any decision about screening, medication or surgery.

  • The guaranteeFull refund within 30 days of ordering, as long as your results haven’t been delivered. Once your results are delivered, the guarantee no longer applies.

  • Your dataWe never sell your genetic data, and we never share it for marketing or research. It goes only to those who complete your order: the laboratory that runs your tests; for an order shipped to New York, the physician or reference laboratory that completes it; and service providers under contract that store your data or prepare your report for us, including Labrynix and SignalPGx, the laboratory-information and reporting software we use. That holds while GeneMatrix+ is active and after it ends.

  • Cancel anytimeCancel anytime online, or by writing to info@genematrix.io. Your reports stay yours; re-reads stop when GeneMatrix+ ends.

Free shipping within the US

Comparing prices? What testing for inherited cancer risk costs

Does GeneCancer check BRCA1 and BRCA2?

It checks selected variants in BRCA1 and BRCA2, among 108 genes, by genotyping. It doesn’t read the whole genes, so a result with none found can’t rule out inherited risk.

If you or a close relative has had cancer, ask your doctor about full-gene clinical testing.

Which genes does GeneCancer check for breast, colon, prostate and pancreatic cancer?

It checks selected variants in 108 genes by genotyping, including BRCA1 and BRCA2. Which of those genes are linked to breast, colon, prostate or pancreatic cancer is general science, set out with its sources in our guide.

It doesn’t check RAD51C, RAD51D or HOXB13.

A result with no variant found can’t rule out inherited cancer risk.

Which genes are linked to which cancers, with sources
Two women, one visibly older, seen from behind, arm in arm along a tree-lined path scattered with autumn leaves.

Who it’s for

It’s for you if

  • You want to know whether you carry any of the specific variants this panel tests for, before talking screening through with your doctor.
  • You want to know whether a finding among those variants could matter for your children or siblings.
  • You want a plain report on those variants to keep, and to bring to your appointments.

It isn’t for

  • It is not a diagnosis, and it cannot tell you whether you have cancer now. If you have symptoms, see your doctor.
  • If you have had cancer, or close relatives had cancer (especially at a young age), ask your doctor or a genetic counselor about clinical testing that reads these genes in full. This panel checks selected variants only.
  • It is not a substitute for a clinician-ordered confirmatory test. A variant found here should be confirmed before any decision is made.
  • If a relative already has a known variant, your doctor can order a test for that exact variant instead.
Two benchtop array scanners on a lab bench, one tray extended, a slide lying beside it.
Illustrative image, not our laboratory.

Our lab

GeneMatrix runs its own CLIA-certified laboratory in Chicago, and every order is tested there except those shipped to New York. These are the people and credentials behind your results.

Laboratory director
Dr. Shawn Desai, Ph.D., J.D., N.R.C.C.
CLIA certificate
14D2276402
Address
1375 W Fulton St, Suite 545, Chicago, IL 60607
See the certificate and the director

How it works

How it works, step by step
  1. Hands opening the GeneMatrix kit box.

    Your kit arrives

    Order online and the kit comes by mail, straight from the lab, with the swab, its tube and everything you need to use it.

  2. A hand capping the sample collection tube.

    Collect at home

    Wait 30 minutes after eating or drinking, then rub the soft swab along your lower gums, 10 times on each side. Seal it in its tube and send it back as the kit explains.

  3. Genotyped in our lab

    Your saliva sample is genotyped in our own CLIA-certified lab in Chicago.

    Orders shipped to New York are completed through a physician order or a reference laboratory permitted in New York.

  4. An older man reading on his phone in a linen armchair by a tall window, seen from behind.

    Your report

    When your results are ready we email you (the email never names your test) with the lab’s secure link to your report, which asks for the tested person’s details before it opens. It is in plain words, to read in your own time.

What’s in your kit

  • The swab and its tubeA soft sponge swab on a cap, and a tube with a little liquid that keeps your sample stable in the post.
  • Step-by-step instructionsPrinted, in plain words, from the wait before you start to the post box.
  • An activation cardYour kit ID, with a QR code and a barcode. Scan it to activate your kit before you mail it.
  • A specimen bagA sealable bag with an absorbent pad inside, which the postal rules ask for.
  • A sealA sticker across the box flap, so it arrives as you closed it.
  • A prepaid return boxThe return box and a prepaid USPS return label. Postage is paid.

Related tests

GenePGx $399 How your genes affect the way you process everyday, pain and mental-health medicines, with a supplement view
Medication Check Tool Type a medicine to see whether published guidance links it to a gene.

Further reading

All articles All guides

Questions

What if a variant is found?

Your report explains the variant, the cancers it is associated with and what to discuss with your doctor. It should be confirmed by a clinician-ordered test before any decision about screening, medication or surgery.

Does no variant found mean I won’t get cancer?

No. It means none of the specific variants this panel tests for was found. Other variants in these same genes, and in genes not on the panel, are not tested and may still be present. Cancer can also develop for other reasons, so keep to the screening your doctor recommends.

Cancer runs in my family. Is this the right test?

If you or a close relative has had cancer, ask your doctor about full-gene clinical testing. A full-gene test reads each gene in full; GeneCancer checks selected variants only.

Should my family be tested too?

Relatives can share an inherited variant. The report explains how the variant is passed on, which you can share with your relatives and their doctors.

How do I give the sample?

With a saliva kit at home. You collect the sample, seal the tube and send it back to our own lab in Chicago, where it is genotyped. Orders shipped to New York are completed through a physician order or a reference laboratory permitted in New York.

Do I need a doctor’s order?

You can order online; self-pay orders don’t need a doctor’s order. Orders shipped to New York are completed through a physician order or a reference laboratory permitted in New York.

If you or a close relative has had cancer, ask your doctor about full-gene clinical testing.

Buy GeneCancer, $399Compare ways to buy

Selected variants only, by genotyping. Not a full-gene test. One price, paid when you order.

Limits

Your saliva sample is genotyped in our own CLIA-certified lab in Chicago (New York orders excepted). Genotyping reads selected positions in the genes on this panel; it does not read every position in those genes, or your whole genome.

How we know: What can a cancer gene panel tell you, and what can it miss?

What it can’t find

  • Variants that are not on its list. That includes most rare variants, and new ones not yet described.
  • Large deletions or duplications, where a whole section of a gene is missing or repeated.

So a result with nothing found does not rule out an inherited cancer risk.

  1. Many cancers arise without any inherited variant, so a result with no variant found is not a reason to skip the screening your doctor recommends.
  2. The panel reads selected positions in the genes it lists. A variant at a position it does not read, or in a gene that is not on the panel, will not be found.

Please read

LabOur genetic tests are laboratory-developed tests performed in our own CLIA-certified laboratory. New York is the exception: orders shipped there are completed through a physician order or a reference laboratory permitted in New York. Our genetic tests have not been cleared or approved by the FDA. Results describe inherited traits and risks and are meant to inform decisions you make with your clinician. They are not a diagnosis.

CancerTesting for inherited cancer risk is a screening test, not a diagnosis. A result with no variant found does not mean you will not develop cancer, and finding a variant does not mean you will. Talk to your doctor or a genetic counselor before making any decision about screening, medication or surgery.

PGxPharmacogenomic results describe how your body is likely to process certain medicines. They do not tell you whether a medicine will work for you, and they are not dosing instructions. Never start, stop or change a medication because of a genetic result. Bring it to the prescriber who manages your medicines.

WellnessOur nutrition, supplement, athletic and wellbeing reports are for general wellness and information. The evidence behind these associations is less established than for our clinical panels, and these reports are not intended to diagnose, treat, cure or prevent any disease.

Who writes our guides, where their facts come from and how to ask for a correction: our editorial policy.

Three generations of women’s hands resting one on another on a linen tablecloth.

Bring a clear report to your next appointment.

$399self-pay price

Selected variants only, by genotyping. Not a full-gene test.

One price, paid when you order.

If you or a close relative has had cancer, ask your doctor about full-gene clinical testing.

Buy GeneCancerSee all tests

Have Medicare, Medicaid, TRICARE or another government health plan? Please contact us before you order.

The first year of GeneMatrix+ is included when you turn on automatic renewal at checkout. After that it’s $99 a year until you cancel. Renewal is charged to your payment method each year. Leave automatic renewal off and you get the test alone, without a GeneMatrix+ year. Cancel anytime online, or by writing to info@genematrix.io. Your reports stay yours.

Testing for inherited cancer risk is a screening test, not a diagnosis. Please read the full note