Skip to main content
Hereditary Cancer Genetic Testing

BRCA1 & BRCA2
Genetic Testing

Know your hereditary breast and ovarian cancer risk with a clinical-grade BRCA test. Results in 5–7 days. Genetic counseling included. Insurance pre-verified.

Order Your BRCA TestSee How It Works
CLIA CertifiedCPT 81432/814335–7 Day ResultsGenetic Counselor Included
NCCN Guidelines

Should You Get a BRCA Test?

The National Comprehensive Cancer Network (NCCN) recommends BRCA1/BRCA2 genetic testing for anyone who meets one or more of these criteria. If any apply to you, your insurance will likely cover the test.

Breast cancer before age 50
Ovarian cancer at any age
Male breast cancer in family
Ashkenazi Jewish ancestry
Multiple breast cancers
Pancreatic cancer in family

Not sure if you qualify? Our team checks your insurance before you order.

BRCA1 / BRCA2

Hereditary Breast & Ovarian Cancer

Breast cancer risk (lifetime)

General population~12%
BRCA positiveUp to 72%

Ovarian cancer risk (lifetime)

General population~1.3%
BRCA positiveUp to 44%

Male breast cancer risk

General population~0.1%
BRCA positiveUp to 7%

Pancreatic cancer risk

General population~1.6%
BRCA positive2–5%

Key insight: Women with a BRCA1 mutation have up to a 72% lifetime risk of breast cancer and up to 44% risk of ovarian cancer. Early detection through enhanced screening can be life-saving.

What You Get With Your BRCA Test

Every BRCA test at Gene Matrix goes far beyond a simple positive/negative result. Here is what is included:

Full BRCA Report

BRCA1 and BRCA2 full gene sequencing plus deletion/duplication analysis. Every exon checked for variants large and small.

Genetic Counseling

A certified genetic counselor walks you through your results, explains what they mean, and helps you build a screening plan.

Insurance Verification

We check your benefits before testing. Most major insurers cover BRCA testing for qualifying patients using CPT 81432 and 81433.

Screening Roadmap

If a variant is found, you get a personalized screening schedule based on NCCN guidelines — mammograms, MRIs, and more.

How the BRCA Test Works

Step 1

Order Online

Choose a subscription plan starting at $69/month. We ship your kit within 24 hours.

Step 2

Collect at Home

Swab the inside of each cheek for 30 seconds. No needles, no blood. Mail back in the prepaid envelope.

Step 3

Lab Analysis

Our CLIA-certified lab sequences BRCA1 and BRCA2 using Illumina next-generation sequencing. Results in 5–7 days.

Step 4

Review Results

View your report online. If positive, schedule a free session with a board-certified genetic counselor.

Included with Essential — $69/mo

Get BRCA1/BRCA2 with Essential Plan

BRCA1/BRCA2 is included in your Essential Plan subscription — along with 10 other genetic tests. No per-test fees. No surprises.

All 11 genetic tests included
AI-powered analysis & insights
HIPAA-secure patient portal
Physician-ready PDF reports
Free DNA kit shipping
Genetic counselor consultations
Subscribe & Get BRCA1/BRCA2 — $69/mo

The Cost Comparison

BRCA1/BRCA2 individually

One-time purchase

$499

Essential Plan — all 11 tests

Monthly subscription

$69/mo

This test individually: $499. With your subscription: included at $69/mo along with 10 other tests.

Compare all 11 tests
Jennifer K.
“My mother had breast cancer at 42. I finally got tested and found out I carry a BRCA2 variant. My doctor immediately put me on an enhanced screening protocol. That test may have saved my life.”

Jennifer K.

Chicago, IL

BRCA2 pathogenic variant detected

Why Get Your BRCA Test at Gene Matrix?

CLIA-certified lab with 99.9% analytical accuracy validated against Sanger sequencing

Results in 5–7 days — faster than most hospital genetics departments

Board-certified genetic counselor included with every positive result

Insurance pre-verification so you know your out-of-pocket cost upfront

Validation: Our BRCA1/BRCA2 sequencing is validated against Sanger sequencing with 100% concordance for known pathogenic variants. The assay detects single nucleotide variants, small insertions/deletions, and large exon-level deletions/duplications across both genes. See our validation documentation.

Insurance & Billing Codes

81432BRCA1/BRCA2 full gene sequence analysis
81433BRCA1/BRCA2 deletion/duplication analysis
96040Genetic counseling (per session)

Most major insurers cover BRCA testing for qualifying patients. We handle pre-authorization and provide superbills for reimbursement.

Frequently Asked Questions

A BRCA test checks for harmful mutations in the BRCA1 and BRCA2 genes, which significantly increase your risk of breast, ovarian, and other cancers. Knowing your status lets you take preventive action — earlier screening, risk-reducing medications, or in some cases, preventive surgery — before cancer develops.
Gene Matrix includes BRCA testing in subscriptions starting at $69/month. Many insurance plans cover the test for individuals who meet NCCN criteria, using CPT codes 81432 (sequencing) and 81433 (deletion/duplication). We verify your coverage before you order so there are no surprises.
You should consider testing if you have: breast cancer before age 50; ovarian cancer at any age; a male relative with breast cancer; Ashkenazi Jewish ancestry; two or more family members with breast, ovarian, or pancreatic cancer; or a known BRCA mutation in a first-degree relative.
Negative: No pathogenic variants found — your risk is similar to the general population. Positive: A pathogenic variant was found — your risk for breast and ovarian cancer is elevated, but you now have the knowledge to take preventive action. Variant of Uncertain Significance (VUS): A change was found but current evidence cannot confirm if it is harmful.
A simple cheek swab you do at home. No needles, no blood draw. Swab both cheeks, seal the tube, and drop it in the prepaid mailer. Most kits arrive within 2 business days of ordering.
Yes — the same type of test that revealed Angelina Jolie carried a BRCA1 mutation. Her choice to share her story brought worldwide attention to hereditary cancer risk, and her proactive decision saved her life. Today, BRCA testing is more accessible and affordable than ever.

Knowledge is Power.

A BRCA test is not just about knowing your risk — it is about taking control. Women who know their BRCA status and follow enhanced screening protocols have dramatically better outcomes.

Get Your BRCA Test — $69/moTalk to a Specialist

Cookie & Privacy Preferences

HIPAA GDPR

We use cookies to ensure our website functions securely and to improve your experience. As a healthcare provider handling sensitive genetic data, we adhere to strict HIPAA and GDPR standards. No personal health information (PHI) is ever stored in cookies. You can customize your preferences below.

Privacy Policy
Gene Matrix AI — Ask me anything