GenePGxPersonalized Medication
Discover which medications work best for YOUR body. GenePGx analyzes 98+ genes to help your doctor prescribe the right drug at the right dose — covering 700+ medications across 10 medical specialties.
Real answers for real medications
Click any medication type below to see exactly what we test — and what it means for someone like you.
Is your pain medication actually doing anything?
Marcus, 44, had been taking codeine for back pain for months with minimal relief. His GenePGx report revealed he's a poor CYP2D6 metabolizer — his body couldn't convert codeine to its active form. His doctor switched him to a different opioid and his pain was finally controlled.
What GenePGx checks for pain relievers
Codeine won't convert to morphine — switch to oxycodone
This is a sample result. Your actual result will be personalized to your DNA.
Does GenePGx cover your medications?
With 724+ medications across 10 specialties, explore how your genes affect the drugs you already take — or may need in the future.
Heart & Blood Pressure
Are your heart meds the right fit?
1 in 3 people carry a variant that changes how they process warfarin
Blood thinners, statins, and blood pressure medications vary dramatically based on your genes. Your DNA can determine if warfarin gives you too much or too little protection — or if a common statin could cause muscle damage.
Your Genes Explain
Why Medications Feel Wrong
If a medication never worked, or worked too well, or made you feel terrible — that's not random. It's your DNA. GenePGx finally gives you answers.
"My antidepressant stopped working. Why?"
This is one of the most common questions we hear — and the answer is almost always in your DNA.
What's Really Happening
If you carry certain variations in your CYP2D6 gene, your liver may break down antidepressants too fast — meaning they leave your body before they can work. Or too slow — meaning they build up and cause side effects.
GenePGx identifies your exact CYP2D6 type so your doctor can choose an antidepressant that actually reaches effective levels in your bloodstream.
"This pain medication makes me feel awful. Is that normal?"
Codeine, tramadol, and opioids affect people very differently — and genetics explain why.
What's Really Happening
Some people convert codeine or tramadol at 10x the normal rate. This floods your system with active drug all at once — causing nausea, dizziness, or even dangerous reactions. Others barely convert it at all, getting zero pain relief.
GenePGx shows exactly how your body converts pain medications, so your doctor can prescribe alternatives that give you effective relief without the misery.
"My blood thinner dose keeps changing. Why can't they get it right?"
Warfarin dosing is notoriously tricky — but for genetically predictable reasons.
What's Really Happening
Two genes — CYP2C9 and VKORC1 — control how fast your body breaks down warfarin AND how sensitive you are to it. Get either one wrong and you're either clotting or bleeding. Doctors often spend months adjusting doses through trial and error.
GenePGx calculates your optimal warfarin starting dose before you take your first pill — the same approach used by major hospital systems and the FDA.
These aren't edge cases. They're everyday situations affecting millions of people.
Find Out Your Medication ProfileWhy Choose GenePGx?
Because your body is not average — and average dosing was never designed for you.
Most prescribing is still
trial and error.
Doctors prescribe a medication and wait to see if it works. If it doesn't — or if it causes side effects — they try another one. Then another. For millions of people, this cycle takes years.
Know before you take.
Not after.
A single cheek swab reveals how your body processes medications — so your doctor can prescribe confidently the first time.
Before & After GenePGx
“Prescribed Plavix for heart disease. Took it for 6 months with no improvement.”
“Genetic test revealed CYP2C19 *2 variant. Doctor switched to Brilinta. Platelet levels normalized in 3 weeks.”
End the guessing game
Your genes explain why some drugs work, others fail, and why you might need a different dose than the "standard."
Protect yourself — and your wallet
Preventable drug reactions cost the healthcare system billions and patients their health. Know your risk before you take a pill.
Science already knows — now you can too
The FDA has already updated drug labels with genetic dosing guidance. GenePGx gives you that knowledge, tailored to your DNA.
One test. A lifetime of better prescribing.
Your DNA never changes. Share your GenePGx report with any provider, anywhere, anytime — no repeat tests needed.
The Gene That Changed
Their Treatment
These are real people who spent years — sometimes decades — on medications that weren't right for them. One test changed everything.
"I spent 8 years on four different antidepressants. Some did nothing, some made me gain 30 pounds, one gave me heart palpitations. Every doctor said "let's try something else." After GenePGx, we discovered I'm a CYP2D6 poor metabolizer — I actually can't process most SSRIs properly. My psychiatrist switched me to a medication that bypasses that enzyme entirely."
First time in 8 years I feel like myself. The medication works exactly the way it's supposed to.
"My cardiologist adjusted my warfarin dose five times in three months. My INR was never in range — I was always either too high (bleeding risk) or too low (clot risk). My son convinced me to do GenePGx. Turns out I carry two gene variants that together make me extremely sensitive to warfarin. My therapeutic dose is actually less than half of what most people need."
Stable INR for 14 months straight. No more weekly blood tests. My cardiologist now recommends PGx for all his anticoagulation patients.
"After my minor heart procedure, I was put on clopidogrel to prevent clots. My interventional cardiologist ordered a follow-up test six months later and saw basically no drug effect at all. We were both concerned. The GenePGx result revealed I'm an ultra-rapid CYP2C19 metabolizer — my body processes the drug so fast it never accumulates to therapeutic levels."
Switched to prasugrel, which doesn't need conversion. My antiplatelet therapy is now working. Could have been a very different outcome.
Get GenePGx with Premium Plan
GenePGx is included in your Premium Plan subscription — along with 10 other genetic tests. No per-test fees. No surprises.
The Cost Comparison
GenePGx individually
One-time purchase
$299
Premium Plan — all 11 tests
Monthly subscription
$89/mo
This test individually: $299. With your subscription: included at $89/mo along with 10 other tests.
GenePGx is just the beginning
Your subscription unlocks all 11 tests. Here are a few more you get at no extra cost:
“I had been on antidepressants for 3 years with no improvement. GenePGx revealed I'm a poor CYP2D6 metabolizer — my body couldn't process the drug. My psychiatrist switched my medication and within 6 weeks I felt like myself again.”
Marcus T.
Houston, TX
CYP2D6 poor metabolizer identified
Choose YourHealth Journey
Comprehensive genetic testing subscriptions with your GeneMatrix AI DNA Kit included
Essential
Perfect for getting started
or $55/mo billed annuallySave 20%
What's included
- 10 Genetic tests per year
- 1 Annual cancer screening (108 genes)
- 1 Annual PGx (pharmacogenomics) test
- 77+ cancer types covered
- Basic pharmacogenomics (50 drugs)
- AI-powered health reports
- Basic risk assessments
- Personalized recommendations
- GeneMatrix mobile app
- Secure health dashboard
- Email support
- Downloadable PDF reports
- Ancestry insights
- Advanced predictive analytics
- Genetic counselor session
- Family health sharing
- Physician portal access
Premium
Most comprehensive coverage
or $71/mo billed annuallySave 20%
What's included
- 10 Genetic tests per year
- 2 Cancer screenings annually (188 genes)
- 2 PGx (pharmacogenomics) tests annually
- 120+ cancer types covered
- Full pharmacogenomics (350+ drugs)
- GeneMind mental health panel
- GeneDiet nutrition analysis
- Advanced AI health reports
- Comprehensive risk assessments
- Predictive health analytics
- Drug interaction alerts
- Priority email & chat support
- 1 Genetic counselor session/year
- Priority 48-hour processing
- Comprehensive PDF reports
- Family health sharing (2 members)
- Physician portal access
Family
Complete family protection
or $111/mo billed annuallySave 20%
What's included
- Coverage for up to 4 family members
- 4 Tests per member per year
- Bi-annual 188-gene screening for all
- 120+ cancer types per member
- Full pharmacogenomics for all
- GeneBaby pediatric panels
- Carrier screening for parents
- Family genetic risk mapping
- Cross-generational insights
- Hereditary condition tracking
- Shared family dashboard
- Dedicated account manager
- 4 Genetic counselor sessions/year
- VIP 24-hour processing
- 24/7 priority support
- Unlimited family sharing
Enterprise Solutions
Custom genetic testing programs for healthcare organizations, employers, and research institutions.
See Exactly WhatYou're Getting
Every single feature, side by side — so there are no surprises when you subscribe.
vs. purchasing 10 individual tests separately at ~$2,750/yr
vs. purchasing every Premium feature individually at ~$6,100/yr
vs. full individual plans for 4 family members at ~$24,400/yr
Questions about which plan fits your health goals?
Talk to a Genetic Counselor — Free ConsultationAll plans include your GeneMatrix AI DNA Kit
Sample Report
Explore a real GenePGx report with detailed pharmacogenomic findings and personalized medication recommendations
Report ID: GPX-2024-59214
Sample Report - For Demonstration Purposes
Drug Metabolism
Clinical Guidelines Referenced
Metabolizer Status Summary
Get the Complete Report
Download the full report with all genetic findings, medication recommendations, and clinical guidance for your healthcare provider
From Swab to
Life-Changing Answers
Getting your pharmacogenomics profile takes less effort than a trip to the pharmacy — and gives you answers you'll use for the rest of your life.
Your Kit Arrives at Your Door
A sleek, lab-ready DNA collection kit shipped directly to you. Everything you need is inside — collection swab, instructions, pre-paid return envelope.
A 90-Second Cheek Swab at Home
No needles. No lab visits. Gently swab the inside of your cheek for 30 seconds each side. Cap the tube, seal the envelope, drop it in any mailbox.
CLIA-Certified Lab Analyzes 98+ Genes
Your sample goes to our CLIA-certified, CAP-accredited laboratory. We sequence every drug metabolism gene — CYP2D6, CYP2C19, CYP2C9, VKORC1, SLCO1B1 and 90+ more — with 99.9% accuracy.
Your Personalized Report Is Ready
In 5-7 days, you receive a detailed, easy-to-read report showing exactly how your body processes each medication class. Share it with any doctor, pharmacist, or specialist — it's yours forever.
Ready in 5-7 Business Days
Start the process today. Results that last a lifetime.
Frequently Asked Questions
Everything you need to know about GenePGx
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Learn More
Explore additional resources about pharmacogenomics and personalized medicine
Latest Research & News
Stay updated on pharmacogenomics breakthroughs, clinical studies, and Gene Matrix innovations
About Gene Matrix
Learn about our mission, CLIA-certified labs, and commitment to precision medicine excellence
FAQ & Support
Get answers to common questions about genetic testing, results interpretation, and insurance coverage
Stop Guessing.
Start Knowing.
Your genes don't change. One GenePGx test gives your doctor the information they need to prescribe confidently — today and every year of your life.
Covered by many insurance plans. HSA/FSA eligible. Share with any provider, anywhere.
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