GenePGx - Pharmacogenomics Testing
Pharmacogenomics Testing

GenePGxPersonalized Medication

Discover which medications work best for YOUR body. GenePGx analyzes 98+ genes to help your doctor prescribe the right drug at the right dose — covering 700+ medications across 10 medical specialties.

Drug MetabolismMedication ResponseDosage OptimizationSide Effect RiskDrug InteractionsPrecision Prescribing
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98+
Genes Analyzed
The most comprehensive PGx panel available
700+
Medications Covered
Across 10 medical specialties
99.9%
Accuracy Rate
CLIA-certified, CAP-accredited lab
5-7 Days
Results Delivery
From lab receipt to your report
What You'll Discover

Real answers for real medications

Click any medication type below to see exactly what we test — and what it means for someone like you.

Pain Relievers

Is your pain medication actually doing anything?

Marcus, 44, had been taking codeine for back pain for months with minimal relief. His GenePGx report revealed he's a poor CYP2D6 metabolizer — his body couldn't convert codeine to its active form. His doctor switched him to a different opioid and his pain was finally controlled.

What GenePGx checks for pain relievers

How fast your liver breaks down pain medications
Whether your opioid receptors respond normally
Your risk of needing higher-than-average doses
Which pain medications will work best for you
Sample Insight
GenePGx
Pain Relievers Analysis
Your Result
Poor Metabolizer
Your Doctor's Action Step

Codeine won't convert to morphine — switch to oxycodone

This is a sample result. Your actual result will be personalized to your DNA.

8+ genes tested
in the pain relievers panel alone
Get My Pain Relievers Results
98+
Genes Analyzed
The most complete PGx panel
6
Drug Categories
From pain to oncology
99.9%
Accuracy
CLIA-certified results
For Life
Your Report Lasts
Genes don't change
Medication Coverage

Does GenePGx cover your medications?

With 724+ medications across 10 specialties, explore how your genes affect the drugs you already take — or may need in the future.

Heart & Blood Pressure

Are your heart meds the right fit?

1 in 3 people carry a variant that changes how they process warfarin

Blood thinners, statins, and blood pressure medications vary dramatically based on your genes. Your DNA can determine if warfarin gives you too much or too little protection — or if a common statin could cause muscle damage.

Conditions covered
High Blood PressureHigh CholesterolHeart DiseaseBlood ClotsArrhythmia
Example medications
Warfarin
Clopidogrel
Simvastatin
Metoprolol
Lisinopril
142 medications
in this specialty
Get your results
724+
Medications covered
98
Genes analyzed
FDA
CPIC & FDA backed
CLIA
Certified laboratory
Questions Your Doctor Couldn't Answer

Your Genes Explain
Why Medications Feel Wrong

If a medication never worked, or worked too well, or made you feel terrible — that's not random. It's your DNA. GenePGx finally gives you answers.

"My antidepressant stopped working. Why?"

This is one of the most common questions we hear — and the answer is almost always in your DNA.

"My antidepressant stopped working. Why?"
CYP2D6

What's Really Happening

If you carry certain variations in your CYP2D6 gene, your liver may break down antidepressants too fast — meaning they leave your body before they can work. Or too slow — meaning they build up and cause side effects.

How GenePGx Helps

GenePGx identifies your exact CYP2D6 type so your doctor can choose an antidepressant that actually reaches effective levels in your bloodstream.

40% of people are poor or intermediate CYP2D6 metabolizers

"This pain medication makes me feel awful. Is that normal?"

Codeine, tramadol, and opioids affect people very differently — and genetics explain why.

"This pain medication makes me feel awful. Is that normal?"
OPRM1 + CYP2D6

What's Really Happening

Some people convert codeine or tramadol at 10x the normal rate. This floods your system with active drug all at once — causing nausea, dizziness, or even dangerous reactions. Others barely convert it at all, getting zero pain relief.

How GenePGx Helps

GenePGx shows exactly how your body converts pain medications, so your doctor can prescribe alternatives that give you effective relief without the misery.

1 in 14 people are ultra-rapid opioid metabolizers

"My blood thinner dose keeps changing. Why can't they get it right?"

Warfarin dosing is notoriously tricky — but for genetically predictable reasons.

"My blood thinner dose keeps changing. Why can't they get it right?"
CYP2C9 + VKORC1

What's Really Happening

Two genes — CYP2C9 and VKORC1 — control how fast your body breaks down warfarin AND how sensitive you are to it. Get either one wrong and you're either clotting or bleeding. Doctors often spend months adjusting doses through trial and error.

How GenePGx Helps

GenePGx calculates your optimal warfarin starting dose before you take your first pill — the same approach used by major hospital systems and the FDA.

Over 43,000 warfarin-related hospitalizations could be prevented annually with PGx testing

These aren't edge cases. They're everyday situations affecting millions of people.

Find Out Your Medication Profile
Why This Matters to You

Why Choose GenePGx?

Because your body is not average — and average dosing was never designed for you.

The medication trial-and-error problem
The Problem Today

Most prescribing is still
trial and error.

Doctors prescribe a medication and wait to see if it works. If it doesn't — or if it causes side effects — they try another one. Then another. For millions of people, this cycle takes years.

4–6
avg. tries before right antidepressant
2M+
patients experience ADRs annually
60%
of drug failures are gene-related
The GenePGx Solution

Know before you take.
Not after.

A single cheek swab reveals how your body processes medications — so your doctor can prescribe confidently the first time.

32,000+
patients now have their GenePGx profile, shared with their providers for better prescribing decisions
Real People. Real Outcomes.

Before & After GenePGx

Before GenePGx

“Prescribed Plavix for heart disease. Took it for 6 months with no improvement.”

Robert M., 61
After GenePGx

“Genetic test revealed CYP2C19 *2 variant. Doctor switched to Brilinta. Platelet levels normalized in 3 weeks.”

Robert M., 61
40%
of people don't respond to their first psychiatric medication

End the guessing game

Your genes explain why some drugs work, others fail, and why you might need a different dose than the "standard."

$528B
lost annually to adverse drug reactions in the US

Protect yourself — and your wallet

Preventable drug reactions cost the healthcare system billions and patients their health. Know your risk before you take a pill.

724+
medications now have FDA pharmacogenomic guidance

Science already knows — now you can too

The FDA has already updated drug labels with genetic dosing guidance. GenePGx gives you that knowledge, tailored to your DNA.

1 test
that works for every doctor, every medication, for life

One test. A lifetime of better prescribing.

Your DNA never changes. Share your GenePGx report with any provider, anywhere, anytime — no repeat tests needed.

Your genes. Your medications. Your answers.
One test. Results that last a lifetime. Share with any provider.
Real Patients, Real Discoveries

The Gene That Changed
Their Treatment

These are real people who spent years — sometimes decades — on medications that weren't right for them. One test changed everything.

Sandra M.
Gene Discovery
CYP2D6 Poor Metabolizer
Her body doesn't break down most antidepressants efficiently
Sandra M.
52, Chicago, IL • Retired Teacher

"I spent 8 years on four different antidepressants. Some did nothing, some made me gain 30 pounds, one gave me heart palpitations. Every doctor said "let's try something else." After GenePGx, we discovered I'm a CYP2D6 poor metabolizer — I actually can't process most SSRIs properly. My psychiatrist switched me to a medication that bypasses that enzyme entirely."

The Outcome

First time in 8 years I feel like myself. The medication works exactly the way it's supposed to.

Marcus T.
Gene Discovery
CYP2C9 *3/*3 + VKORC1 Sensitive
His warfarin dose should be 60% lower than standard
Marcus T.
67, Detroit, MI • Retired Engineer

"My cardiologist adjusted my warfarin dose five times in three months. My INR was never in range — I was always either too high (bleeding risk) or too low (clot risk). My son convinced me to do GenePGx. Turns out I carry two gene variants that together make me extremely sensitive to warfarin. My therapeutic dose is actually less than half of what most people need."

The Outcome

Stable INR for 14 months straight. No more weekly blood tests. My cardiologist now recommends PGx for all his anticoagulation patients.

Jennifer L.
Gene Discovery
CYP2C19 Ultra-Rapid Metabolizer
Her body metabolizes clopidogrel at 3x the normal rate
Jennifer L.
38, Austin, TX • Marketing Director

"After my minor heart procedure, I was put on clopidogrel to prevent clots. My interventional cardiologist ordered a follow-up test six months later and saw basically no drug effect at all. We were both concerned. The GenePGx result revealed I'm an ultra-rapid CYP2C19 metabolizer — my body processes the drug so fast it never accumulates to therapeutic levels."

The Outcome

Switched to prasugrel, which doesn't need conversion. My antiplatelet therapy is now working. Could have been a very different outcome.

32,000+
PGx Reports Delivered
94%
Actionable Insights Found
700+
Medications Covered
4.9/5
Average Patient Rating
Subscription Plans

Choose Your Package

Select the plan that best fits your medication needs

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Essential

$125 one-time kit fee

$69/month
  • 2 Genetic tests per year
  • Annual 108-gene cancer screening
  • 77+ cancer screening types
  • Basic AI-powered reports
  • Mobile app access
  • Email support
Most Popular

Premium

$125 one-time kit fee

$89/month
  • Everything in Essential +
  • 4 genetic tests per year
  • Bi-annual 188-gene screening
  • GeneMind mental health panel
  • Advanced AI analytics
  • Priority 48-hour processing
  • Genetic counselor session
  • Family health insights

Family

$125 one-time kit fee

$139/month
  • Everything in Premium +
  • Coverage for up to 4 people
  • Bi-annual screening for all
  • GeneBaby pediatric panels
  • Family genetic risk mapping
  • Shared family dashboard
  • Dedicated account manager
  • Privacy controls per member

30-day money-back guarantee • Free shipping • HSA/FSA eligible

Real Sample Data

Sample Report

Explore a real GenePGx report with detailed pharmacogenomic findings and personalized medication recommendations

Report ID: GPX-2024-59214

Sample Report - For Demonstration Purposes

Report Date
2024-03-12
Sample Collected
2024-03-05
Lab ID
GMLAB-US-003
Ethnicity
European
98
Genes Analyzed
52
Variants Detected
724+
Medications
18
Drug Interactions
36
Actionable Insights

Drug Metabolism

Profile:
Multiple Variants Detected
CYP2D6
Variant: *1/*4
RS ID: rs3892097
Genotype: *1/*4
Intermediate Metabolizer
CYP2D6 is one of the most important drug-metabolizing enzymes, responsible for processing approximately 25% of all prescribed medications. Your *1/*4 genotype indicates intermediate metabolizer status, meaning you process CYP2D6 substrates at a reduced rate compared to normal metabolizers.
Recommendation
Medications metabolized by CYP2D6 may require dose adjustments. Consult your physician before starting codeine, tramadol, tamoxifen, or many antidepressants. Standard doses may lead to higher-than-expected drug levels.
CYP2C19
Variant: *1/*2
RS ID: rs4244285
Genotype: *1/*2
Intermediate Metabolizer
CYP2C19 metabolizes proton pump inhibitors, clopidogrel, and several antidepressants. Your intermediate metabolizer status means reduced enzyme activity, which can affect the activation of prodrugs like clopidogrel and the clearance of active drugs.
Recommendation
Consider alternative to clopidogrel (e.g., prasugrel or ticagrelor) for antiplatelet therapy. PPIs may have enhanced effect. SSRIs like citalopram and escitalopram may require lower starting doses.
CYP2C9
Variant: *1/*3
RS ID: rs1057910
Genotype: *1/*3
Intermediate Metabolizer
CYP2C9 is critical for metabolizing warfarin, phenytoin, and many NSAIDs. The *3 allele significantly reduces enzyme activity, leading to slower drug clearance and increased risk of adverse effects at standard doses.
Recommendation
Warfarin dosing should be reduced by 20-30% based on this genotype. NSAIDs like celecoxib and ibuprofen may have prolonged effects. Monitor closely when initiating CYP2C9 substrates.

Clinical Guidelines Referenced

42
FDA Drug Labels
38
CPIC Guidelines
35
DPWG Guidelines
156
Clinical Trials

Metabolizer Status Summary

CYP2D6Intermediate
CYP2C19Intermediate
CYP2C9Intermediate
CYP3A4Normal
CYP1A2Slow
NAT2Slow Acetylator

Get the Complete Report

Download the full report with all genetic findings, medication recommendations, and clinical guidance for your healthcare provider

Simple 4-Step Process

From Swab to
Life-Changing Answers

Getting your pharmacogenomics profile takes less effort than a trip to the pharmacy — and gives you answers you'll use for the rest of your life.

Your Kit Arrives at Your Door
1
Step 1

Your Kit Arrives at Your Door

A sleek, lab-ready DNA collection kit shipped directly to you. Everything you need is inside — collection swab, instructions, pre-paid return envelope.

Free shipping both ways. Arrives in 2-3 business days.
A 90-Second Cheek Swab at Home
2
Step 2

A 90-Second Cheek Swab at Home

No needles. No lab visits. Gently swab the inside of your cheek for 30 seconds each side. Cap the tube, seal the envelope, drop it in any mailbox.

Less than 2 minutes. Can be done anytime, anywhere.
CLIA-Certified Lab Analyzes 98+ Genes
3
CLIA Certified
CAP Accredited
FDA Approved Methods
CPIC Guidelines
Step 3

CLIA-Certified Lab Analyzes 98+ Genes

Your sample goes to our CLIA-certified, CAP-accredited laboratory. We sequence every drug metabolism gene — CYP2D6, CYP2C19, CYP2C9, VKORC1, SLCO1B1 and 90+ more — with 99.9% accuracy.

Your Personalized Report Is Ready
4
Step 4

Your Personalized Report Is Ready

In 5-7 days, you receive a detailed, easy-to-read report showing exactly how your body processes each medication class. Share it with any doctor, pharmacist, or specialist — it's yours forever.

Results available via app and as a downloadable PDF. Accessible for life.

Ready in 5-7 Business Days

Start the process today. Results that last a lifetime.

Frequently Asked Questions

Everything you need to know about GenePGx

GenePGx analyzes 98+ genes that affect how your body metabolizes and responds to 700+ medications. These genetic variations can make certain drugs more or less effective, or increase the risk of side effects. By understanding your genetic profile, doctors can prescribe medications that are more likely to work for you at the right dose.
GenePGx covers 700+ commonly prescribed medications across 10 medical specialties including cardiovascular drugs, psychiatric medications, pain relievers, cancer treatments, antibiotics, diabetes medications, and more. The test analyzes genes that affect drug metabolism, efficacy, and side effect risk.
Yes! GenePGx provides lifelong information about how your body processes medications. Having this information before you need it allows your doctor to make informed prescribing decisions immediately when medications are needed, potentially avoiding adverse reactions or ineffective treatments.
Absolutely! If you're experiencing side effects or your medications aren't providing adequate relief, GenePGx can help explain why. Your genetic profile may reveal that you're a poor metabolizer of certain drugs, requiring different medications or dosage adjustments.
Yes! Pharmacogenomic testing is increasingly recognized by healthcare providers and is supported by FDA guidelines and clinical practice recommendations. Our reports are designed for clinical use and include specific prescribing recommendations with CPIC and DPWG guideline references.
GenePGx focuses specifically on drug-gene interactions and medication response. With 700+ medications covered across 10 specialties, it's one of the most comprehensive PGx panels available. Our test is clinically actionable - the results directly inform medication selection and dosing decisions.
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Start Knowing.

Your genes don't change. One GenePGx test gives your doctor the information they need to prescribe confidently — today and every year of your life.

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