Pain Pathways
Medical Visualization
Advanced Pain Genetics

GenePain

Decode Your Pain Response

Understand your genetic predisposition to pain sensitivity, medication response, and inflammation. Get personalized pain management strategies based on your unique DNA profile.

Pain Sensitivity
Opioid Response
Inflammation
NSAID Metabolism
Nerve Function
Recovery Rate
CLIA Certified
HIPAA Compliant
98% Accuracy

Pain Genetics Analysis

150+
Genes Analyzed
85+
Pain Markers
40+
Medications
98%
Accuracy
Pain SensitivityHigh Impact
Opioid ResponseModerate
Inflammation RiskElevated
Scroll to Explore
Comprehensive Analysis

Genes We Test

GenePain analyzes 150+ genes across 6 critical pain-related categories to provide a complete picture of your pain genetics

150+ Genes
6 Categories
98% Accuracy

Pain Sensitivity

28 genes

Genes that influence how intensely you perceive pain signals and your overall pain threshold.

SCN9A
SCN10A
SCN11A
COMT
OPRM1
+ 23 more genes analyzed in this category
Full gene list available in your personalized report
Learn more

Opioid Response

22 genes

Genetic variants affecting how your body metabolizes and responds to opioid-based pain medications.

OPRM1
ABCB1
CYP2D6
CYP3A4
UGT2B7
+ 17 more genes analyzed in this category
Full gene list available in your personalized report
Learn more

Inflammation Pathways

25 genes

Genes controlling inflammatory responses that contribute to chronic pain and tissue damage.

IL6
TNF
IL1B
COX2
NF-kB
+ 20 more genes analyzed in this category
Full gene list available in your personalized report
Learn more

NSAID Metabolism

18 genes

Variants that determine how effectively you process common over-the-counter pain relievers.

CYP2C9
CYP2C8
UGT1A6
PTGS1
PTGS2
+ 13 more genes analyzed in this category
Full gene list available in your personalized report
Learn more

Nerve Function

30 genes

Genes involved in nerve signal transmission, neuropathic pain, and peripheral nerve health.

TRPV1
TRPA1
P2RX7
CACNA1B
KCNQ2
+ 25 more genes analyzed in this category
Full gene list available in your personalized report
Learn more

Recovery & Healing

27 genes

Genetic factors that influence tissue repair speed, wound healing, and post-injury recovery.

GCH1
BDNF
FKBP5
ADRB2
MC1R
+ 22 more genes analyzed in this category
Full gene list available in your personalized report
Learn more
All analyses performed in our CLIA-certified and CAP-accredited laboratories
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Subscription Packages

Select the perfect plan for your pain management journey

MonthlyAnnualSave 20%

Essential

$125 one-time kit fee

$69/month
Save 71% vs individual tests
  • 2 Genetic tests per year
  • Annual 108-gene cancer screening
  • 77+ cancer screening types
  • Basic AI-powered reports
  • Mobile app access
  • Email support
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Premium

$125 one-time kit fee

$89/month
Save 84% vs individual tests
  • Everything in Essential +
  • 4 genetic tests per year
  • Bi-annual 188-gene screening
  • Gene Mind mental health panel
  • Advanced AI analytics
  • Priority 48-hour processing
  • Genetic counselor session
  • Family health insights

Family

$125 one-time kit fee

$139/month
Save 93% vs individual tests
  • Everything in Premium +
  • Coverage for up to 4 people
  • Bi-annual screening for all
  • Gene Baby pediatric panels
  • Family genetic risk mapping
  • Shared family dashboard
  • Dedicated account manager
  • Privacy controls per member
For Organizations

EnterpriseCustom Solutions

$299/month

+ $75 per employee kit fee

Volume DiscountsROI AnalysisCustom Integration
Unlimited employee testing
Bi-annual 188-gene screening
Corporate wellness dashboard
Custom genetic panels
EHR/wellness integration
Population health analytics
White-label capabilities
Research collaboration
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256-bit Encryption
30-Day Money Back
24/7 Support
Real Sample Data

Sample Report

Explore a comprehensive GenePain report with detailed genetic insights for pain management

Report ID
GP-2024-789456
Collection Date
2024-01-15
Report Date
2024-02-01
42
Genes Analyzed
18
Variants Detected
12
Recommendations
6
Categories
21
Gene Findings

Pain Sensitivity Findings

COMT

Variant: Val158Met
rsID: rs4680
Genotype: Val/Met
Moderate Impact

The COMT gene affects pain sensitivity through dopamine metabolism. Your Val/Met genotype indicates moderate pain sensitivity with balanced pain perception.

Recommendation:

Maintain regular pain management strategies. Consider mindfulness and cognitive behavioral therapy for chronic pain conditions.

SCN9A

Variant: R1150W
rsID: rs6746030
Genotype: G/A
High Impact

SCN9A encodes sodium channels critical for pain signal transmission. Your variant is associated with increased pain sensitivity and lower pain threshold.

Recommendation:

Work closely with pain specialists. Consider multimodal pain management approaches including physical therapy and nerve blocks when appropriate.

OPRM1

Variant: A118G
rsID: rs1799971
Genotype: A/G
Moderate Impact

This variant in the mu-opioid receptor gene affects pain perception and opioid response. Your genotype suggests moderate pain sensitivity with good opioid efficacy.

Recommendation:

Standard opioid dosing may be effective. Monitor response and adjust as needed under medical supervision.

GCH1

Variant: Pain-protective haplotype
rsID: rs8007267
Genotype: C/T
Low Impact

GCH1 variants influence pain sensitivity through tetrahydrobiopterin production. Your genotype provides some protection against chronic pain development.

Recommendation:

Maintain healthy lifestyle habits to support natural pain resilience. Focus on preventive strategies for pain management.

Pharmacogenomics Preview

Opioids

Codeine
Standard dosing
Morphine
May need higher doses

NSAIDs

Ibuprofen
Reduced initial dose
Naproxen
Reduced initial dose

Pain Management Plan

Lifestyle Recommendations

  • Anti-Inflammatory Diet: Increase omega-3 fatty acids: fatty fish (salmon, mackerel, ...
  • Exercise and Movement: Engage in low-impact aerobic exercise 30 minutes daily (walk...
  • Stress Management: Practice daily meditation or mindfulness for 10-20 minutes...

Therapy Suggestions

  • Physical Therapy
  • Acupuncture
  • Massage Therapy

Get the full comprehensive report with all findings, recommendations, and personalized insights

Ready to Get Your Own Report?

Order your GenePain test today and receive personalized insights for optimal pain management

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