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Clinical genetics, kept current

GeneMatrix: genetic tests you collect at home. We run them in our own CLIA-certified lab (New York orders excepted) and explain every result in plain English.

Full refund within 30 days of ordering, as long as your results haven’t been delivered.

The GeneMatrix saliva collection kit: a sealed collection tube beside its box, on a stone plinth.
  • CLIA 14D2276402
  • Our own lab · Chicago (New York orders excepted)
  • Your genetic data is never sold, and never shared for marketing or research
  • Reports yours to keep
  • Free shipping within the US

The tests

Your genetic tests come in one kit; Oral Health DNA has its own kit, and GeneBaby uses a separate gentle swab along your baby’s gums. Buy the one you need.

Your genetic tests come in one kit; Oral Health DNA has its own kit, and GeneBaby uses a separate gentle swab along your baby’s gums.

Nutrigenomics

GeneCoreAll-in-one$499one-time

Your diet, fitness and everyday health traits, together in one wellness report

Genetic traits studied in diet, fitness and everyday wellbeing, set out side by side in one report.

One-time payment. Self-pay only. We don’t bill insurance for this test.

Our nutrition, supplement, athletic and wellbeing reports are for general wellness and information. The evidence behind these associations is less established than for our clinical panels, and these reports are not intended to diagnose, treat, cure or prevent any disease.

GeneDiet$199one-time

How your genetics relate to carbohydrates, fats, appetite, taste, caffeine and lactose

Genetic traits studied in nutrient metabolism and diet response.

One-time payment. Self-pay only. We don’t bill insurance for this test.

Our nutrition, supplement, athletic and wellbeing reports are for general wellness and information. The evidence behind these associations is less established than for our clinical panels, and these reports are not intended to diagnose, treat, cure or prevent any disease.

GeneSport$199one-time

Genetic traits studied in training response, recovery and injury

Traits studied in athletic performance, training response and injury.

One-time payment. Self-pay only. We don’t bill insurance for this test.

Our nutrition, supplement, athletic and wellbeing reports are for general wellness and information. The evidence behind these associations is less established than for our clinical panels, and these reports are not intended to diagnose, treat, cure or prevent any disease.

GeneHealth$199one-time

Genetic traits studied in everyday health and wellbeing

Wellness traits and the associations studied for them, for general information.

One-time payment. Self-pay only. We don’t bill insurance for this test.

Our nutrition, supplement, athletic and wellbeing reports are for general wellness and information. The evidence behind these associations is less established than for our clinical panels, and these reports are not intended to diagnose, treat, cure or prevent any disease.

GeneResilience$199one-time

Genetic traits studied in stress response, sleep timing and antioxidant defences

Traits studied in how people respond to stress, and in sleep timing, for general information.

One-time payment. Self-pay only. We don’t bill insurance for this test.

Our nutrition, supplement, athletic and wellbeing reports are for general wellness and information. The evidence behind these associations is less established than for our clinical panels, and these reports are not intended to diagnose, treat, cure or prevent any disease.

Pharmacogenomics

GenePGxSelected variants only, by genotyping. Not a full-gene test.$399self-pay price

How your genes affect the way you process everyday, pain and mental-health medicines, with a supplement view

How you are likely to process medicines that have published pharmacogenomic guidance.

Checks selected known variants in 15 genes, plus CYP2D6 copy number, by genotyping.

One price, paid when you order. We don’t send a claim to your health insurance.

Pharmacogenomic results describe how your body is likely to process certain medicines. They do not tell you whether a medicine will work for you, and they are not dosing instructions. Never start, stop or change a medication because of a genetic result. Bring it to the prescriber who manages your medicines.

GeneCancer

GeneCancerSelected variants only, by genotyping. Not a full-gene test.$399self-pay price

Genotyping of selected inherited variants linked to higher cancer risk

Whether you carry any of the specific inherited variants this panel tests for that are associated with higher cancer risk.

Checks selected variants across 108 genes, including BRCA1 and BRCA2, by genotyping.

One price, paid when you order. Selected variants only, by genotyping. Not a full-gene test.

Testing for inherited cancer risk is a screening test, not a diagnosis. A result with no variant found does not mean you will not develop cancer, and finding a variant does not mean you will. Talk to your doctor or a genetic counselor before making any decision about screening, medication or surgery.

If you or a close relative has had cancer, ask your doctor about full-gene clinical testing.

  • Have Medicare, Medicaid, TRICARE or another government health plan? Please contact us before you order. Contact us

For families

GeneBaby$399one-time

Inherited conditions screened from birth, alongside state newborn screening

Inherited conditions screened in a newborn, to discuss with your pediatrician.

One-time payment. Self-pay only. We don’t bill insurance for this test.

GeneBaby does not replace the newborn screening your state performs at birth, and it is not a diagnostic test. Deciding to test a child is a decision to make with your pediatrician.

  • At checkout, a parent or legal guardian confirms they are ordering for their baby.
A woman brushing her teeth at a bathroom mirror in the morning.

New

  • An oral microbiome test: one easy saliva sample shows which bacteria linked to gum disease and cavities are in your mouth, and how much. Results in about five business days after the lab receives your activated sample.
  • $199 includes the kit, prepaid return shipping and the lab analysis.

Self-pay only. We don’t bill insurance for this test.

See Oral Health DNA

How it works

  1. Hands opening the GeneMatrix kit box.

    01

    Order

    Choose a test and pay the self-pay price. Insurance billing for GenePGx is coming soon. We ship within the US for now; email us about other countries.

  2. A hand capping the sample collection tube.

    02

    Collect

    Wait 30 minutes after eating or drinking, then rub the soft swab along your lower gums, 10 times on each side. Seal it in its tube and send it back as the kit explains. For GeneBaby, a gentle swab along your baby’s gums instead.

  3. A clear plate of tiny sample spots on a dark instrument stage, lit by a narrow beam of light.

    03

    Genotyped in our lab

    Your sample is genotyped in our own CLIA-certified lab in Chicago.

    Orders shipped to New York are completed through a physician order or a reference laboratory permitted in New York.

    Illustrative image, not our laboratory.

  4. 04

    Read, then re-read

    Your reports arrive through the lab’s secure link, which we email you. With GeneMatrix+, they are re-read automatically whenever the evidence from our sources is updated.

The Living Read

Read once. Kept current.

  1. 01

    Genotyped once.

    Collected once, at home. Our lab reads the positions on your panels once (New York orders excepted), because your DNA does not change.

  2. 02

    Re-read as the evidence updates.

    Published guidance and evidence sources are updated over time. With GeneMatrix+, your results are re-read automatically whenever the evidence from our sources is updated. The first year of GeneMatrix+ is included when you turn on automatic renewal at checkout.

  3. 03

    Yours to keep.

    Every report stays yours if you cancel GeneMatrix+. Re-reads stop when it ends.

24 chromosomes, to scale · marked: genes with published clinical guidance

Your report

Every result says what was found, what it means, and what to bring to your clinician. Nothing to decode.

See the full sample report

Medication response

Illustrative example

3
genes
shown
  • CYP2C19Intermediate metabolizer
  • CYP2D6Intermediate metabolizer
  • SLCO1B1Decreased function
  • CYP2C19*1/*2

    Intermediate metabolizer

    Guidance exists for: clopidogrel, citalopram, sertraline

  • CYP2D6*1/*4

    Intermediate metabolizer

    Guidance exists for: codeine, tramadol, ondansetron

  • SLCO1B1rs4149056 T/C

    Decreased function

    Guidance exists for: simvastatin, atorvastatin

Pharmacogenomic results describe how your body is likely to process certain medicines. They do not tell you whether a medicine will work for you, and they are not dosing instructions. Never start, stop or change a medication because of a genetic result. Bring it to the prescriber who manages your medicines.

GeneCancer · Hereditary cancer

None of the pathogenic or likely pathogenic variants tested was detected.

Testing for inherited cancer risk is a screening test, not a diagnosis. A result with no variant found does not mean you will not develop cancer, and finding a variant does not mean you will. Talk to your doctor or a genetic counselor before making any decision about screening, medication or surgery.

Medication Check

Type a generic medication name. We’ll show whether published CPIC guidance links it to a gene.

Pharmacogenomic results describe how your body is likely to process certain medicines. They do not tell you whether a medicine will work for you, and they are not dosing instructions. Never start, stop or change a medication because of a genetic result. Bring it to the prescriber who manages your medicines.

Sealed sample tubes in a rack on a white bench.
Illustrative image, not our laboratory.

Our lab

GeneMatrix runs its own CLIA-certified laboratory in Chicago, and every order is tested there except those shipped to New York. These are the people and credentials behind your results.

Laboratory director
Dr. Shawn Desai, Ph.D., J.D., N.R.C.C.
CLIA certificate
14D2276402
Address
1375 W Fulton St, Suite 545, Chicago, IL 60607
Inside the lab

Our Privacy Promise

  • Never sold.
  • Never shared for marketing or research.
  • Yours to keep.

We never sell your genetic data, and we never share it for marketing or research. It goes only to those who complete your order: the laboratory that runs your tests; for an order shipped to New York, the physician or reference laboratory that completes it; and service providers under contract that store your data or prepare your report for us, including Labrynix and SignalPGx, the laboratory-information and reporting software we use. Once we can bill health plans, and only if you choose to bill our pharmacogenomics (PGx) test to yours, your health plan receives what it needs to process that claim, and for no other purpose. Nutrigenomics and oral microbe results never go to a health plan. Your reports stay yours, even if you cancel. Who sees your data.

Pricing

Every test has one self-pay price, and it is the price you pay at checkout.

  • Clinical tests

    Medicines and inherited cancer risk

    • self-pay price

      One price, paid when you order. We don’t send a claim to your health insurance.

      Insurance billing is coming soon.How insurance billing will work

    • Selected variants only, by genotyping. Not a full-gene test.self-pay price

      One price, paid when you order. If you or a close relative has had cancer, ask your doctor about full-gene clinical testing.

    Have Medicare, Medicaid, TRICARE or another government health plan? Please contact us before you order.

  • Nutrigenomics

    Diet, fitness and everyday health

    One-time payment. Self-pay only. We don’t bill insurance for this test. For general wellness and information, not diagnosis.

  • For families

    For your newborn

    One-time payment. Self-pay only. We don’t bill insurance for this test. At checkout, a parent or legal guardian confirms they are ordering for their baby.

  • Oral Health DNA

    Measures microbes, not your genes.

    One-time payment. Self-pay only. We don’t bill insurance for this test.

GeneMatrix+

First year included when you turn on automatic renewal at checkout. After that it’s $99 a year until you cancel.

GeneMatrix+ re-reads your genetic results automatically whenever the evidence from our sources is updated, and sends you the updated report. Oral Health DNA measures microbes, not your genes, so it does not include GeneMatrix+.

Renewal is charged to your payment method each year. Leave automatic renewal off and you get the test alone, without a GeneMatrix+ year. Cancel anytime online, or by writing to info@genematrix.io. Your reports stay yours.

About GeneMatrix+

Full refund within 30 days of ordering, as long as your results haven’t been delivered.

See every test →

DNA and blood

Blood panels are repeated because your body changes. Your genome doesn’t, so it only needs to be read once. Many people use both.

GeneMatrix compared with Function Health, Superpower and 23andMe
GeneMatrixFunction HealthSuperpower23andMe
SampleSaliva, from a gentle gum swab at home (your baby’s own, for GeneBaby)Blood drawBlood drawSaliva, at home
What it readsSelected inherited genetic variants, by genotyping160+ lab tests a year150+ lab tests across 2 drawsGenotyping array, consumer reports
How oftenOnce, then re-read with GeneMatrix+Twice a yearTwice a yearOnce
Published price$199–$499 per test$365 a year$349 a year$99–$199 kits

Other companies’ details as published on their websites, checked 22 September 2026. Prices and inclusions change; check their sites. Sources: functionhealth.com, superpower.com, 23andme.com.

Questions

I already do blood testing. Why DNA?

Blood panels show how your body is doing now, so they are repeated. Your genome doesn’t change, so it only needs to be read once. Many people use both.

What is the guarantee?

Full refund within 30 days of ordering, as long as your results haven’t been delivered. Once your results are delivered, the guarantee no longer applies.

Can I use insurance?

Not today. Every test has one self-pay price, paid when you order, and when you pay yourself we don’t send a claim to your health insurance. Insurance billing for GenePGx is coming soon.

Which tests are self-pay only?

GeneCore, GeneCancer, GeneBaby, GeneDiet, GeneSport, GeneHealth, GeneResilience and Oral Health DNA are self-pay only: we don’t bill insurance for these tests. Insurance billing for GenePGx is coming soon. Every test has one self-pay price, paid when you order.

Do I need a doctor’s order?

You can order online; self-pay orders don’t need a doctor’s order. If insurance billing opens, your own clinician will need to order the test. Orders shipped to New York are completed through a physician order or a reference laboratory permitted in New York.

What is GeneMatrix+?

GeneMatrix+ re-reads your genetic results automatically whenever the evidence from our sources is updated, and sends you the updated report. The first year of GeneMatrix+ is included when you turn on automatic renewal at checkout. After that it’s $99 a year until you cancel. Renewal is charged to your payment method each year. Leave automatic renewal off and you get the test alone, without a GeneMatrix+ year. Cancel anytime online, or by writing to info@genematrix.io. Your reports stay yours.

Do you sell my genetic data, or share it for marketing or research?

No. We never sell your genetic data, and we never share it for marketing or research. It goes only to those who complete your order: the laboratory that runs your tests; for an order shipped to New York, the physician or reference laboratory that completes it; and service providers under contract that store your data or prepare your report for us, including Labrynix and SignalPGx, the laboratory-information and reporting software we use. Once we can bill health plans, and only if you choose to bill our pharmacogenomics (PGx) test to yours, your health plan receives what it needs to process that claim, and for no other purpose. Nutrigenomics and oral microbe results never go to a health plan.

Where do you ship?

We ship within the US for now; email us at info@genematrix.io about other countries. Prices are in US dollars.

Is this a diagnosis?

Our genetic tests are laboratory-developed tests performed in our own CLIA-certified laboratory. New York is the exception: orders shipped there are completed through a physician order or a reference laboratory permitted in New York. Our genetic tests have not been cleared or approved by the FDA. Results describe inherited traits and risks and are meant to inform decisions you make with your clinician. They are not a diagnosis.

Please read

Please read

LabOur genetic tests are laboratory-developed tests performed in our own CLIA-certified laboratory. New York is the exception: orders shipped there are completed through a physician order or a reference laboratory permitted in New York. Our genetic tests have not been cleared or approved by the FDA. Results describe inherited traits and risks and are meant to inform decisions you make with your clinician. They are not a diagnosis.

WellnessOur nutrition, supplement, athletic and wellbeing reports are for general wellness and information. The evidence behind these associations is less established than for our clinical panels, and these reports are not intended to diagnose, treat, cure or prevent any disease.

PGxPharmacogenomic results describe how your body is likely to process certain medicines. They do not tell you whether a medicine will work for you, and they are not dosing instructions. Never start, stop or change a medication because of a genetic result. Bring it to the prescriber who manages your medicines.

CancerTesting for inherited cancer risk is a screening test, not a diagnosis. A result with no variant found does not mean you will not develop cancer, and finding a variant does not mean you will. Talk to your doctor or a genetic counselor before making any decision about screening, medication or surgery.

NewbornGeneBaby does not replace the newborn screening your state performs at birth, and it is not a diagnostic test. Deciding to test a child is a decision to make with your pediatrician.

NoteOral Health DNA is a laboratory-developed test performed in our own CLIA-certified laboratory. New York is the exception: orders shipped there are completed through a physician order or a reference laboratory permitted in New York. It has not been cleared or approved by the FDA. It measures the DNA of microbes in your saliva, not your DNA: it is not a genetic test, not a diagnosis, and not a prediction of any disease.

The GeneMatrix kit, box open and the collection tube beside it.

Start at home.

Full refund within 30 days of ordering, as long as your results haven’t been delivered.