GeneCore Comprehensive Genetic Health Screening
Most Comprehensive Genetic Test

GeneCoreComplete Health Screening

One simple cheek swab. 130+ genes analyzed. A 45-page roadmap written in plain English that tells you exactly what your DNA means for your heart, metabolism, brain, immune system, bones, and how your body processes medications.

Cardiovascular HealthMetabolic FunctionImmune SystemDetoxificationBone HealthCognitive Function
CLIA Certified Lab
HIPAA Compliant
Free Shipping
Explore
130+
Genes Analyzed
Most comprehensive panel available
6
Health Categories
Heart, metabolism, brain & more
99.9%
Lab Accuracy
CLIA-certified results you can trust
45+
Page Report
Plain English — no jargon
Plain English Insights

What Your DNA Actually Tells You

Not raw data and gene codes — real answers to questions you've probably been asking your whole life.

"Why do I gain weight even when I eat well?"
"Why do I gain weight even when I eat well?"

Your FTO and MC4R genes control hunger signals and fat storage. Some people are genetically wired to feel hungrier, store more fat, and burn fewer calories — no matter what they do.

Recommendation

GeneCore tells you exactly which metabolic variants you carry and which diet type matches your DNA.

"Why do I feel exhausted even after 8 hours of sleep?"
"Why do I feel exhausted even after 8 hours of sleep?"

MTHFR gene variants block your body from converting folic acid to its active form, causing low energy, brain fog, and poor recovery. About 1 in 3 people carry this variant and don't know it.

Recommendation

GeneCore identifies methylation gene variants and recommends the exact supplement form your body can actually use.

"Should I be worried about my heart as I get older?"
"Should I be worried about my heart as I get older?"

The APOE gene — carried by 25% of the population — significantly raises cardiovascular and Alzheimer's risk. Most people discover it too late. Early detection changes your prevention strategy.

Recommendation

GeneCore analyzes 25 cardiovascular genes and gives you a personalized prevention plan years before symptoms appear.

6 Health Categories

Every Area of Your Health. Covered.

130+ genes analyzed across 6 categories — each one revealing something actionable about your health.

Cardiovascular Health
25 genes

Cardiovascular Health

Will your heart thank you or warn you?

Learn if you carry variants that raise cholesterol, affect blood pressure, or increase clotting risk — so you can act before symptoms appear.

What you\'ll discover
Your natural LDL cholesterol tendency
Blood pressure genetic risk factors
Heart attack & stroke predisposition
Response to heart medications
APOEMTHFRACEAGTCETP+20 more
Metabolic Function
30 genes

Metabolic Function

Why some diets work for others but not you.

Your metabolism is written in your DNA. Discover why you may store fat differently, how your body processes sugar, and which diet type actually fits your genes.

What you\'ll discover
Weight gain & fat storage tendencies
Blood sugar regulation & diabetes risk
How your body uses carbs vs fats
Metabolism speed & calorie burning
FTOMC4RPPARGTCF7L2ADIPOQ+25 more
Immune System
20 genes

Immune System

Why do you get sick more — or less — than others?

Your immune genes determine how aggressively your body fights infection, manages inflammation, and responds to autoimmune triggers. This changes everything about prevention.

What you\'ll discover
Inflammatory response strength
Autoimmune condition susceptibility
Infection & virus resistance
Allergy & sensitivity predispositions
HLA-BIL6TNFIFNGCCR5+15 more
Detoxification
18 genes

Detoxification

How well does your liver actually clean your blood?

Your detox genes control how fast you process caffeine, alcohol, medications, and environmental toxins. Some people are slow metabolizers — and never know it.

What you\'ll discover
Caffeine metabolism speed
Alcohol & toxin processing ability
Medication clearance rate
Environmental chemical sensitivity
CYP1A2CYP2C9GSTM1GSTT1NAT2+13 more
Bone Health
15 genes

Bone Health

Are your bones silently losing density?

Bone loss is invisible until it breaks. Your genes reveal your vitamin D absorption, calcium metabolism, and osteoporosis risk — decades before a fracture.

What you\'ll discover
Vitamin D receptor efficiency
Calcium absorption capacity
Osteoporosis & fracture risk
Joint & collagen strength genes
VDRCOL1A1LRP5ESR1CALCR+10 more
Cognitive Function
22 genes

Cognitive Function

How long will your mind stay sharp?

Your brain genes affect memory, focus, mood regulation, and long-term dementia risk. The APOE gene alone can significantly shift your Alzheimer's probability.

What you\'ll discover
Memory & learning gene variants
Alzheimer's & dementia risk factors
Focus, mood & dopamine genetics
Stress resilience & mental fatigue
BDNFCOMTAPOEKIBRACHRNA4+17 more

From Swab to Life-Changing Insights

The entire process takes about 5 minutes of your time. We handle everything else.

Order Your Kit
1

Order Your Kit

Choose your plan and we'll ship a simple collection kit right to your door — usually in 2-3 business days.

Free express shipping both ways. No appointment needed. No lab visit.
Swab at Home
2

Swab at Home

The kit contains a simple cheek swab. Takes less than 2 minutes. No needles, no blood, no hassle.

Simple, painless, and done in under 2 minutes from your couch.
Mail It Back
3

Mail It Back

Seal your sample in the prepaid return envelope and drop it in any mailbox. We handle everything from there.

Prepaid shipping label included. Drop it in any mailbox — done.
Read Your Results
4

Read Your Results

Your 45+ page personalized report lands in your secure online portal, with a plain-English breakdown of every finding.

Plain English explanations. No PhD required to understand your results.
GeneMatrix CLIA Certified Lab
Processed in a CLIA-Certified, CE-IVD Certified Lab

Your sample is analyzed using next-generation sequencing (NGS) technology — the same technology used by top hospitals and research institutions. Every result is reviewed by board-certified geneticists before delivery.

CLIA Certified
CE-IVD
HIPAA
GDPR

Real People. Real Discoveries.

What GeneCore customers found out — and what they did about it.

Sarah M.
Sarah M., 44
Chicago, IL
MTHFR C677T variant detected

“I'd struggled with fatigue and brain fog for years. My GeneCore results showed I have a MTHFR variant that blocks folic acid absorption. Switching to methylfolate supplements changed my life within 6 weeks.”

David K.
David K., 52
Houston, TX
APOE ε3/ε4 variant identified

“Finding out I carry an APOE4 variant wasn't scary — it was empowering. I completely changed my diet, started exercising daily, and now my cardiologist is impressed with my numbers at 52.”

Jennifer R.
Jennifer R., 38
Denver, CO
CYP1A2 slow metabolizer found

“I was drinking 4 cups of coffee a day wondering why I couldn't sleep. Turns out I'm a slow caffeine metabolizer. Cut to 1 cup before noon — I sleep 8 hours now and feel incredible.”

10,000+
Reports Delivered
4.9/5
Average Rating
94%
Found Actionable Insights
GeneCore genetic health report
Your 45+ Page Report
Written in plain English. Reviewed by geneticists.
What\'s In Your Report

A 45-Page Guide Written For You

No confusing lab codes. No unexplained numbers. Every page tells you what was found, what it means in everyday language, and exactly what you should do next.

6 Category Risk Summaries
Each health area gets a clear overall risk rating — Low, Moderate, or High — with a plain-English explanation.
Gene-by-Gene Breakdown
Every significant variant explained: what gene, what variant, what it means, and the science behind it.
28+ Actionable Recommendations
Specific steps — supplements to take, foods to avoid, doctors to see, lifestyle changes that match your DNA.
Medication Compatibility Guide
Which common medications your body processes differently — critical to share with your doctor.
Your Personalized Nutrition Plan
Exact macronutrient ratios and food recommendations based on your metabolic gene profile.
Monitoring Checklist
A personalized schedule of which tests and screenings to get, and when, based on your risks.
Included with Essential — $69/mo

Get GeneCore with Essential Plan

GeneCore is included in your Essential Plan subscription — along with 10 other genetic tests. No per-test fees. No surprises.

All 11 genetic tests included
AI-powered analysis & insights
HIPAA-secure patient portal
Physician-ready PDF reports
Free DNA kit shipping
Genetic counselor consultations
Subscribe & Get GeneCore — $69/mo

The Cost Comparison

GeneCore individually

One-time purchase

$599

Essential Plan — all 11 tests

Monthly subscription

$69/mo

This test individually: $599. With your subscription: included at $69/mo along with 10 other tests.

Compare all 11 tests
Also Included in Your Essential Plan

GeneCore is just the beginning

Your subscription unlocks all 11 tests. Here are a few more you get at no extra cost:

David K.
“Finding out I carry an APOE4 variant wasn't scary — it was empowering. I completely changed my diet, started exercising daily, and now my cardiologist is impressed with my numbers at 52. GeneCore gave me the roadmap I needed.”

David K.

Houston, TX

APOE ε3/ε4 variant identified

Subscription Plans

Choose YourHealth Journey

Comprehensive genetic testing subscriptions with your GeneMatrix AI DNA Kit included

MonthlyAnnualSave 20%

Essential

Perfect for getting started

$69/month

or $55/mo billed annuallySave 20%

Save 70% vs individual tests
10
Tests/Year
108
Cancer Genes
1
Person

What's included

  • 10 Genetic tests per year
  • 1 Annual cancer screening (108 genes)
  • 1 Annual PGx (pharmacogenomics) test
  • 77+ cancer types covered
  • Basic pharmacogenomics (50 drugs)
  • AI-powered health reports
  • Basic risk assessments
  • Personalized recommendations
  • GeneMatrix mobile app
  • Secure health dashboard
  • Email support
  • Downloadable PDF reports
  • Ancestry insights
  • Advanced predictive analytics
  • Genetic counselor session
  • Family health sharing
  • Physician portal access
Most Popular

Premium

Most comprehensive coverage

$89/month

or $71/mo billed annuallySave 20%

Save 82% vs individual tests
10
Tests/Year
188
Cancer Genes
1
Person

What's included

  • 10 Genetic tests per year
  • 2 Cancer screenings annually (188 genes)
  • 2 PGx (pharmacogenomics) tests annually
  • 120+ cancer types covered
  • Full pharmacogenomics (350+ drugs)
  • GeneMind mental health panel
  • GeneDiet nutrition analysis
  • Advanced AI health reports
  • Comprehensive risk assessments
  • Predictive health analytics
  • Drug interaction alerts
  • Priority email & chat support
  • 1 Genetic counselor session/year
  • Priority 48-hour processing
  • Comprehensive PDF reports
  • Family health sharing (2 members)
  • Physician portal access

Family

Complete family protection

$139/month

or $111/mo billed annuallySave 20%

Save 93% vs individual tests
4
Tests/Year
188
Cancer Genes
4
Members

What's included

  • Coverage for up to 4 family members
  • 4 Tests per member per year
  • Bi-annual 188-gene screening for all
  • 120+ cancer types per member
  • Full pharmacogenomics for all
  • GeneBaby pediatric panels
  • Carrier screening for parents
  • Family genetic risk mapping
  • Cross-generational insights
  • Hereditary condition tracking
  • Shared family dashboard
  • Dedicated account manager
  • 4 Genetic counselor sessions/year
  • VIP 24-hour processing
  • 24/7 priority support
  • Unlimited family sharing
For Organizations

Enterprise Solutions

Custom genetic testing programs for healthcare organizations, employers, and research institutions.

$299
/month base + $75/employee
HIPAA Compliant
256-bit Encryption
30-Day Money Back
24/7 Support
Full Plan Breakdown

See Exactly WhatYou're Getting

Every single feature, side by side — so there are no surprises when you subscribe.

Feature
Essential
$69/mo
Most Popular
Premium
$89/mo
Family
$139/mo
Genetic tests per year
Total individual genetic panels you can run annually
10 tests
10 tests
4 per member (16 total)
GeneCore — Core Health Panel
Cardiovascular, metabolic, diabetes, and longevity markers
GenePain — Pain & Inflammation
Chronic pain sensitivity, opioid metabolism, inflammation markers
GeneSport — Athletic Performance
VO2 max potential, muscle fiber type, recovery genetics
GeneHealth — Preventive Health
Hormonal balance, immune function, metabolic health
Annual cancer screenings
Number of comprehensive hereditary cancer tests per year
1 screening / year
2 screenings / year
2 per member / year
Genes analyzed per screening
Breadth of hereditary cancer gene panel
108 genes
188 genes
188 genes
Cancer types covered
Total distinct cancer types screened
77+ types
120+ types
120+ types
Hereditary risk tracking
Track cancer risk trends over multiple test cycles
Family cancer risk mapping
Cross-generational hereditary cancer risk visualization
PGx tests per year
How many times your drug-gene interactions are assessed annually
1 test / year
2 tests / year
2 per member / year
Drugs analyzed
Number of medications mapped to your unique genetics
50 drugs
350+ drugs
350+ drugs
Drug interaction alerts
Real-time alerts when new prescriptions may conflict with your genetics
GenePharma advanced panel
Specialty medications, biologics, oncology drugs
GeneMind — Mental Health Panel
Depression, anxiety, ADHD, psychiatric medication response
GeneDiet — Nutrition & Metabolism
Personalized macronutrient needs, food sensitivities, vitamin metabolism
GeneBaby — Pediatric Panel
Developmental milestones, childhood disease risk, newborn screening
GeneResilience — Stress & Longevity
Cortisol metabolism, telomere markers, longevity genes
Carrier screening for parents
Identify recessive disease genes before or during family planning
Health report quality
Depth and clinical detail of your generated genetic reports
Standard reports
Advanced AI reports
Advanced AI reports
Risk assessment depth
Breadth of risk factors modeled in your health profile
Basic (12 categories)
Comprehensive (40+)
Comprehensive (40+)
Predictive health analytics
AI models that project future health risks based on genetics + lifestyle
Ancestry & trait insights
Population ancestry breakdown and trait predictions
Basic ancestry
Deep ancestry + 200 traits
Deep ancestry + 200 traits
Cross-generational insights
AI analysis of inherited risk patterns across your family tree
Downloadable PDF reports
Full clinical-grade PDF you can share with your doctor
Health update frequency
How often your risk scores and insights are refreshed
Annual updates
Quarterly updates
Monthly updates
Family sharing
Share your genomic dashboard with trusted family members
2 members
Unlimited
Physician portal access
Secure portal for your doctor to view and annotate your reports
Shared family dashboard
Unified health view for all covered family members
Results turnaround
Time from sample receipt to final report delivery
14–21 business days
Priority 48 hours
VIP 24 hours
Support channels
How you can reach the GeneMatrix support team
Email support
Email + Live chat
24/7 Priority line
Genetic counselor sessions
Live consultations with a certified genetic counselor
1 session / year
4 sessions / year
Dedicated account manager
Personal point of contact for all your account needs
GeneMatrix mobile app
iOS & Android app for tracking results and health scores
Save 66%
Essential Plan

vs. purchasing 10 individual tests separately at ~$2,750/yr

Save 82%
Premium Plan

vs. purchasing every Premium feature individually at ~$6,100/yr

Save 93%
Family Plan

vs. full individual plans for 4 family members at ~$24,400/yr

Questions about which plan fits your health goals?

Talk to a Genetic Counselor — Free Consultation
Choose Your Plan

All plans include your GeneMatrix AI DNA Kit

Annual billingMonthly
Real Sample Data

Explore a Real GeneCore Report

Click through each category to see exactly what your results will look like — real genes, real findings, real recommendations.

Report ID: GC-2024-78392

Sample Report — For Demonstration Purposes Only

Report Date
2024-01-29
Sample Collected
2024-01-15
Lab ID
GMLAB-US-001
Ethnicity
European
134
Genes Analyzed
47
Variants Detected
3
High Risk
12
Moderate Risk
28
Actionable Insights

Cardiovascular Health

Overall Risk:
Moderate
APOE
Variant: ε3/ε4 • rs429358 • Genotype: C/T
Moderate Risk

Increased risk for cardiovascular disease and Alzheimer's disease

Recommendation
Regular cardiovascular monitoring, Mediterranean diet, omega-3 supplementation
MTHFR
Variant: C677T • rs1801133 • Genotype: C/T
Moderate Risk

Reduced enzyme activity affecting homocysteine metabolism

Recommendation
Folate supplementation (methylfolate form), B-vitamin complex
ACE
Variant: I/D • rs4340 • Genotype: I/D
Normal

Balanced ACE enzyme activity

Recommendation
Standard cardiovascular health practices

Medication Compatibility

Warfarin
CYP2C9, VKORC1
May require lower dose - consult physician
Clopidogrel
CYP2C19
Normal response expected
Statins
SLCO1B1
Standard dosing appropriate

Your Nutrition Blueprint

35-40%
Carbs
30-35%
Protein
25-30%
Fats
Increase omega-3 fatty acids (2-3g EPA/DHA daily)
Methylfolate supplementation (800-1000 mcg daily)
Limit caffeine to <200mg per day

See the Full 45-Page Report

Download the complete sample including all 6 categories, medication compatibility, nutrition plan, exercise guide, and monitoring checklist.

Your DNA Has Answers. Are You Ready to Listen?

Join 10,000+ people who found out exactly what their genes say — and took control of their health with real, personalized knowledge.

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24/7 Support
HIPAA Compliant

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