GeneCore Comprehensive Genetic Health Screening
Most Comprehensive Genetic Test

GeneCoreComplete Health Screening

One simple cheek swab. 130+ genes analyzed. A 45-page roadmap written in plain English that tells you exactly what your DNA means for your heart, metabolism, brain, immune system, bones, and how your body processes medications.

Cardiovascular HealthMetabolic FunctionImmune SystemDetoxificationBone HealthCognitive Function
CLIA Certified Lab
HIPAA Compliant
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Explore
130+
Genes Analyzed
Most comprehensive panel available
6
Health Categories
Heart, metabolism, brain & more
99.9%
Lab Accuracy
CLIA-certified results you can trust
45+
Page Report
Plain English — no jargon
Plain English Insights

What Your DNA Actually Tells You

Not raw data and gene codes — real answers to questions you've probably been asking your whole life.

"Why do I gain weight even when I eat well?"
"Why do I gain weight even when I eat well?"

Your FTO and MC4R genes control hunger signals and fat storage. Some people are genetically wired to feel hungrier, store more fat, and burn fewer calories — no matter what they do.

How GeneCore Helps

GeneCore tells you exactly which metabolic variants you carry and which diet type matches your DNA.

"Why do I feel exhausted even after 8 hours of sleep?"
"Why do I feel exhausted even after 8 hours of sleep?"

MTHFR gene variants block your body from converting folic acid to its active form, causing low energy, brain fog, and poor recovery. About 1 in 3 people carry this variant and don't know it.

How GeneCore Helps

GeneCore identifies methylation gene variants and recommends the exact supplement form your body can actually use.

"Should I be worried about my heart as I get older?"
"Should I be worried about my heart as I get older?"

The APOE gene — carried by 25% of the population — significantly raises cardiovascular and Alzheimer's risk. Most people discover it too late. Early detection changes your prevention strategy.

How GeneCore Helps

GeneCore analyzes 25 cardiovascular genes and gives you a personalized prevention plan years before symptoms appear.

6 Health Categories

Every Area of Your Health. Covered.

130+ genes analyzed across 6 categories — each one revealing something actionable about your health.

Cardiovascular Health
25 genes

Cardiovascular Health

Will your heart thank you or warn you?

Learn if you carry variants that raise cholesterol, affect blood pressure, or increase clotting risk — so you can act before symptoms appear.

What you\'ll discover
Your natural LDL cholesterol tendency
Blood pressure genetic risk factors
Heart attack & stroke predisposition
Response to heart medications
APOEMTHFRACEAGTCETP+20 more
Metabolic Function
30 genes

Metabolic Function

Why some diets work for others but not you.

Your metabolism is written in your DNA. Discover why you may store fat differently, how your body processes sugar, and which diet type actually fits your genes.

What you\'ll discover
Weight gain & fat storage tendencies
Blood sugar regulation & diabetes risk
How your body uses carbs vs fats
Metabolism speed & calorie burning
FTOMC4RPPARGTCF7L2ADIPOQ+25 more
Immune System
20 genes

Immune System

Why do you get sick more — or less — than others?

Your immune genes determine how aggressively your body fights infection, manages inflammation, and responds to autoimmune triggers. This changes everything about prevention.

What you\'ll discover
Inflammatory response strength
Autoimmune condition susceptibility
Infection & virus resistance
Allergy & sensitivity predispositions
HLA-BIL6TNFIFNGCCR5+15 more
Detoxification
18 genes

Detoxification

How well does your liver actually clean your blood?

Your detox genes control how fast you process caffeine, alcohol, medications, and environmental toxins. Some people are slow metabolizers — and never know it.

What you\'ll discover
Caffeine metabolism speed
Alcohol & toxin processing ability
Medication clearance rate
Environmental chemical sensitivity
CYP1A2CYP2C9GSTM1GSTT1NAT2+13 more
Bone Health
15 genes

Bone Health

Are your bones silently losing density?

Bone loss is invisible until it breaks. Your genes reveal your vitamin D absorption, calcium metabolism, and osteoporosis risk — decades before a fracture.

What you\'ll discover
Vitamin D receptor efficiency
Calcium absorption capacity
Osteoporosis & fracture risk
Joint & collagen strength genes
VDRCOL1A1LRP5ESR1CALCR+10 more
Cognitive Function
22 genes

Cognitive Function

How long will your mind stay sharp?

Your brain genes affect memory, focus, mood regulation, and long-term dementia risk. The APOE gene alone can significantly shift your Alzheimer's probability.

What you\'ll discover
Memory & learning gene variants
Alzheimer's & dementia risk factors
Focus, mood & dopamine genetics
Stress resilience & mental fatigue
BDNFCOMTAPOEKIBRACHRNA4+17 more

From Swab to Life-Changing Insights

The entire process takes about 5 minutes of your time. We handle everything else.

Order Your Kit
1

Order Your Kit

Choose your plan and we'll ship a simple collection kit right to your door — usually in 2-3 business days.

Free express shipping both ways. No appointment needed. No lab visit.
Swab at Home
2

Swab at Home

The kit contains a simple cheek swab. Takes less than 2 minutes. No needles, no blood, no hassle.

Simple, painless, and done in under 2 minutes from your couch.
Mail It Back
3

Mail It Back

Seal your sample in the prepaid return envelope and drop it in any mailbox. We handle everything from there.

Prepaid shipping label included. Drop it in any mailbox — done.
Read Your Results
4

Read Your Results

Your 45+ page personalized report lands in your secure online portal, with a plain-English breakdown of every finding.

Plain English explanations. No PhD required to understand your results.
GeneMatrix CLIA Certified Lab
Processed in a CLIA-Certified, CE-IVD Certified Lab

Your sample is analyzed using next-generation sequencing (NGS) technology — the same technology used by top hospitals and research institutions. Every result is reviewed by board-certified geneticists before delivery.

CLIA Certified
CE-IVD
HIPAA
GDPR

Real People. Real Discoveries.

What GeneCore customers found out — and what they did about it.

Sarah M.
Sarah M., 44
Chicago, IL
MTHFR C677T variant detected

“I'd struggled with fatigue and brain fog for years. My GeneCore results showed I have a MTHFR variant that blocks folic acid absorption. Switching to methylfolate supplements changed my life within 6 weeks.”

David K.
David K., 52
Houston, TX
APOE ε3/ε4 variant identified

“Finding out I carry an APOE4 variant wasn't scary — it was empowering. I completely changed my diet, started exercising daily, and now my cardiologist is impressed with my numbers at 52.”

Jennifer R.
Jennifer R., 38
Denver, CO
CYP1A2 slow metabolizer found

“I was drinking 4 cups of coffee a day wondering why I couldn't sleep. Turns out I'm a slow caffeine metabolizer. Cut to 1 cup before noon — I sleep 8 hours now and feel incredible.”

47,000+
Reports Delivered
4.9/5
Average Rating
94%
Found Actionable Insights
GeneCore genetic health report
Your 45+ Page Report
Written in plain English. Reviewed by geneticists.
What\'s In Your Report

A 45-Page Guide Written For You

No confusing lab codes. No unexplained numbers. Every page tells you what was found, what it means in everyday language, and exactly what you should do next.

6 Category Risk Summaries
Each health area gets a clear overall risk rating — Low, Moderate, or High — with a plain-English explanation.
Gene-by-Gene Breakdown
Every significant variant explained: what gene, what variant, what it means, and the science behind it.
28+ Actionable Recommendations
Specific steps — supplements to take, foods to avoid, doctors to see, lifestyle changes that match your DNA.
Medication Compatibility Guide
Which common medications your body processes differently — critical to share with your doctor.
Your Personalized Nutrition Plan
Exact macronutrient ratios and food recommendations based on your metabolic gene profile.
Monitoring Checklist
A personalized schedule of which tests and screenings to get, and when, based on your risks.
Real Sample Data

Explore a Real GeneCore Report

Click through each category to see exactly what your results will look like — real genes, real findings, real recommendations.

Report ID: GC-2024-78392

Sample Report — For Demonstration Purposes Only

Report Date
2024-01-29
Sample Collected
2024-01-15
Lab ID
GMLAB-US-001
Ethnicity
European
134
Genes Analyzed
47
Variants Detected
3
High Risk
12
Moderate Risk
28
Actionable Insights

Cardiovascular Health

Overall Risk:
Moderate
APOE
Variant: ε3/ε4 • rs429358 • Genotype: C/T
Moderate Risk

Increased risk for cardiovascular disease and Alzheimer's disease

Recommendation
Regular cardiovascular monitoring, Mediterranean diet, omega-3 supplementation
MTHFR
Variant: C677T • rs1801133 • Genotype: C/T
Moderate Risk

Reduced enzyme activity affecting homocysteine metabolism

Recommendation
Folate supplementation (methylfolate form), B-vitamin complex
ACE
Variant: I/D • rs4340 • Genotype: I/D
Normal

Balanced ACE enzyme activity

Recommendation
Standard cardiovascular health practices

Medication Compatibility

Warfarin
CYP2C9, VKORC1
May require lower dose - consult physician
Clopidogrel
CYP2C19
Normal response expected
Statins
SLCO1B1
Standard dosing appropriate

Your Nutrition Blueprint

35-40%
Carbs
30-35%
Protein
25-30%
Fats
Increase omega-3 fatty acids (2-3g EPA/DHA daily)
Methylfolate supplementation (800-1000 mcg daily)
Limit caffeine to <200mg per day

See the Full 45-Page Report

Download the complete sample including all 6 categories, medication compatibility, nutrition plan, exercise guide, and monitoring checklist.

Subscription Plans

Choose Your Package

One-time kit fee + monthly subscription for ongoing genetic insights, screenings, and support.

MonthlyAnnual Save 20%

Essential

$125 one-time kit fee

$69/month
  • 2 Genetic tests per year
  • Annual 108-gene cancer screening
  • 77+ cancer screening types
  • Basic AI-powered reports
  • Mobile app access
  • Email support
Most Popular

Premium

$125 one-time kit fee

$89/month
  • Everything in Essential +
  • 4 genetic tests per year
  • Bi-annual 188-gene screening
  • GeneMind mental health panel
  • Advanced AI analytics
  • Priority 48-hour processing
  • Genetic counselor session
  • Family health insights

Family

$125 one-time kit fee

$139/month
  • Everything in Premium +
  • Coverage for up to 4 people
  • Bi-annual screening for all
  • GeneBaby pediatric panels
  • Family genetic risk mapping
  • Shared family dashboard
  • Dedicated account manager
  • Privacy controls per member
30-day money-back guarantee • Free shipping both ways • HSA/FSA eligible

Your Questions, Answered

Everything you need to know before your first test.

GeneCore is our comprehensive genetic health screening that analyzes 130+ genes across 6 major health categories: cardiovascular, metabolism, immune function, detoxification, bone health, and cognitive function. Written in plain English, your report tells you exactly what your genes mean for your daily health — from the foods you should eat to the medications that work best for your body.
GeneCore uses next-generation sequencing technology with 99.9% accuracy. All samples are processed in our CLIA-certified and CE-IVD Certified laboratories, and results are reviewed by board-certified geneticists before they ever reach you.
Essential plan: 2 weeks. Premium plan: 1 week. Family plan: 48 hours. You'll receive an email the moment your report is ready, with a link to access it through your secure online portal.
Absolutely. We use 256-bit encryption for all data. Your genetic information is never sold or shared with third parties without your explicit consent. We are fully HIPAA and GDPR compliant, and you can request deletion of your data at any time.
Yes! You can download a PDF report or grant your doctor direct portal access. Many physicians actively use GeneCore results to guide treatment decisions. We also offer a free genetic counselor consultation with Premium and Family plans.
Not at all. Every finding in your GeneCore report is written in plain English with practical recommendations. No science degree required. We explain what each gene variant means for your day-to-day life, what it means for your future, and exactly what you can do about it.
Coverage varies by provider and plan. We provide detailed receipts for insurance submission. Our team can also help verify your coverage before ordering. GeneCore is also HSA/FSA eligible.

Your DNA Has Answers. Are You Ready to Listen?

Join 47,000+ people who found out exactly what their genes say — and took control of their health with real, personalized knowledge.

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